NCT07060534: BEST-U

Building Healthy Eating and Self-Esteem Together for University Students

Recruiting now NA Last updated 14 January 2026

What this trial tests

NA trial testing Building Healthy Eating and Self-Esteem Together for University Students in Eating Disorders (Excluding Anorexia Nervosa) in 74 participants. Currently enrolling.

Timeline

23 June 2026

Primary endpoint
31 December 2027

31 December 2027

Quick facts

Lead sponsor	University of Kansas
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	74
Start date	23 June 2026
Primary completion	31 December 2027
Estimated completion	31 December 2027
Sites	1 location across United States

Drugs / interventions tested

• Building Healthy Eating and Self-Esteem Together for University Students
• Present-Centered Therapy

Conditions studied

• Eating Disorders (Excluding Anorexia Nervosa) — all drugs for Eating Disorders (Excluding Anorexia Nervosa) →
• Binge-Eating Disorder — all drugs for Binge-Eating Disorder →

Sponsor

University of Kansas

Who can join

Adults 18 to 65, any sex, with Eating Disorders (Excluding Anorexia Nervosa) or Binge-Eating Disorder. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Eating disorders (EDs) are a critical concern on college campuses. Moreover, since the COVID-19 pandemic, ED prevalence has increased by 62% in university women and 140% in university men. Resources are inadequate to meet demand, leading to delays in students' access to treatment. Untreated (or poorly treated) EDs result in greater healthcare utilization and costs to students, as well as lower academic achievement and increased psychiatric disability and mortality, suggesting a critical need for quality ED treatment on university campuses and to rethink treatment delivery. One way to address this gap in care delivery is to improve treatment accessibility and scalability, such as dissemination via mobile apps. Guided self-help Cognitive Behavior Therapy (CBT-gsh) is a cost-effective option that can be delivered by non-traditional service providers, such as nurses and physicians. Our scientific premise is that the mHealth CBT-gsh app, Building Healthy Eating and Self-Esteem Together for University Students (BEST-U), will lead to reductions in binge eating (primary outcome) through reductions in dietary restraint and weight/shape concerns (target mechanisms). Prior to implementing BEST-U at other universities, we need to test the intervention in a real-world setting with the end goal of disseminating at scale. Our objectives are to: 1) conduct an effectiveness test of BEST-U compared to a similar dose of present-centered therapy (PCT) in students with non-low weight binge-spectrum EDs and 2) test target mechanisms that lead to changes in binge eating. To accomplish our objectives, we will test the following specific aims: 1) conduct an RCT of BEST-U (N=37) compared to a similar dose of PCT (N=37) in students with non-low weight binge-spectrum EDs; 2) test target mechanisms that lead to changes in binge eating and other ED symptoms; and 3) characterize barriers and facilitators to implementation across two campuses. Our exploratory aim will test food reinforcement and food-choice impulsivity as potential target mechanisms or response moderators of rapid response in binge eating. Given that few studies have identified underlying mechanisms that explain how CBT-gsh works and for whom, this study may lead to improved ability to tailor or modify existing CBT-gsh or lead to novel intervention development for students who are unlikely to respond rapidly (or at all) to first line CBT interventions for EDs.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.