Who is sponsoring NCT06017167?

NCT06017167 is sponsored by Tanta University.

What drugs are being tested in NCT06017167?

Interventions in NCT06017167: Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline ., Ondansetron 4mg + dexamethasone 8mg + normal saline..

What condition does NCT06017167 study?

NCT06017167 studies Postoperative Nausea and Vomiting, Laparoscopic Cholecystectomy.

Is NCT06017167 still recruiting?

NCT06017167 is currently status unknown. Last updated 26 August 2023.

Last reviewed 2023-08-26 · How we verify

NCT06017167

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Dexmedetomidine Versus Dexamethasone Adding to Ondansetron for Prophylaxis Against Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy

Status unknown Phase 2 Last updated 26 August 2023

What this trial tests

Phase 2 trial testing Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline . in Postoperative Nausea and Vomiting in 70 participants. Status unknown.

Timeline

15 September 2022

Primary endpoint
1 September 2023

1 October 2023

Quick facts

Lead sponsor	Tanta University
Phase	Phase 2
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	70
Start date	15 September 2022
Primary completion	1 September 2023
Estimated completion	1 October 2023
Sites	1 location across Egypt

Drugs / interventions tested

Ondansetron 4mg + dexmedetomidine 0.5 ug/kg + normal saline . — full drug profile →
Ondansetron 4mg + dexamethasone 8mg + normal saline. — full drug profile →

Conditions studied

Postoperative Nausea and Vomiting — all drugs for Postoperative Nausea and Vomiting →
Laparoscopic Cholecystectomy — all drugs for Laparoscopic Cholecystectomy →

Sponsor

Tanta University

Who can join

Adults 18 to 65, female only, with Postoperative Nausea and Vomiting or Laparoscopic Cholecystectomy. Patients with the condition only — healthy volunteers not accepted.

What's being measured

Primary outcomes are the specific endpoints the trial is designed to prove or disprove.

The incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy.
Time frame: through out 24 hours after surgery.
The incidence of vomiting, use of rescue antiemetics, and analgesic requirements were recorded at 0 to 1 hours after surgery in the postanesthetic care unit (PACU)At 6 and 24 hours after surgery, the incidence and severity of PONV were assessed using the Rhodes Index of nausea, vomiting, and retching.

Sponsor's own description

The aim of the study is to compare antiemetic effects between dexmedetomidine and ondansteron in the first group versus dexamethasone and ondansteron in the second group. The primary outcome in this study is incidence of postoperative nausea and vomiting after laparoscopic cholecystectomy. The secondary outcomes are: * The severity of post operative nausea and vomiting. * Use of rescue antiemetic drugs. * Postoperative pain and sedation.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06017167 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tanta University
Last refreshed: 26 August 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06017167.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing