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NCT05894629
Effects of an Active Coping Program in Patients With Persistent Post-Covid Pain.
NA trial testing Pain Neuroscience Education (PNE)+ Therapeutic Exercise (TE) in Long COVID in 89 participants. Completed in 30 September 2023.
1 June 2023
Quick facts
| Lead sponsor | University of Valladolid |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 89 |
| Start date | 20 February 2023 |
| Primary completion | 1 June 2023 |
| Estimated completion | 30 September 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Pain Neuroscience Education (PNE)+ Therapeutic Exercise (TE)
- Active Comparator: Usual treatment
Conditions studied
- Long COVID — all drugs for Long COVID →
- Pain — all drugs for Pain →
Sponsor
University of Valladolid
Who can join
Adults 18 to 65, any sex, with Long COVID or Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Justification: among the sequelae of Covid-19 in clinical practice we frequently find persistent neuromusculoskeletal pain. Previous studies carried out by this research group and in the scientific literature have shown that "Pain Neuroscience Education" (PNE) and Therapeutic Exercise (TE) constitute an effective care strategy in the treatment of persistent pain. Therefore, with this research we will try to respond with a treatment proposal from Primary Care (PC). Objective: to determine whether an PNE and TE program is effective in patients presenting Long Covid Pain (LCP). Method: Randomized clinical trial. A sample of 80 subjects will be recruited. The intervention group will receive a program of TE and PNE, of 12 weeks duration: 5 weeks of PNE, of 1 weekly session of 90 minutes, and 7 weeks of TE, with a total of 19 sessions of 60 minutes duration. The control group will receive the usual treatment. An assessment will be made at the beginning and after the end of the intervention, where the following variables will be measured: quality of life, intensity, distribution and expansion of pain, healthy physical condition and blood test values. These will be evaluated by means of physical examination, questionnaires and laboratory tests. Applicability of the expected results: The proposed intervention is simple and reproducible. It requires few resources, and can produce changes in pain perception, functionality and quality of life in patients with LCP.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05894629
- Europe PMC full search
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Related trials
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- NCT07278206 — Brain Stimulation in Long COVID · NA · recruiting
Other University of Valladolid trials
Trials by the same sponsor.
- NCT07302191 — High-Intensity Interval or Concurrent Exercise on Oxidative Stress and Inflammation in Obese Women · NA · completed
- NCT07307391 — Exercise in Extreme Hot Weather Conditions · NA · completed
- NCT06696378 — Melatonin Supplementation and Exercise Program in Breast Cancer Women · NA · recruiting
- NCT06616181 — TDCS and Tele-rehabilitation Exercise in Fibromyalgia · NA · not yet recruiting
- NCT06326229 — Clinical Validation of Musculoskeletal ICF Core Set in Primary Care Physiotherapy · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05894629 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Valladolid
- Last refreshed: 4 June 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05894629.
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