Last reviewed · How we verify
NCT07307391: EXHOTCON
Exercise in Extreme Hot Weather Conditions
NA trial testing hot wet high (HWH) in Heat Acclimation and Thermotolerance in 6 participants. Completed in 12 December 2025.
10 December 2025
Quick facts
| Lead sponsor | University of Valladolid |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 6 |
| Start date | 7 July 2025 |
| Primary completion | 10 December 2025 |
| Estimated completion | 12 December 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- hot wet high (HWH)
- hot dry high (HDH)
- Experimental: hot dry low (HWL)
- Experimental: hot wet low (HWL)
Conditions studied
- Heat Acclimation and Thermotolerance — all drugs for Heat Acclimation and Thermotolerance →
- Heat Effect — all drugs for Heat Effect →
Sponsor
University of Valladolid
Who can join
Adults 18 to 50, any sex, with Heat Acclimation and Thermotolerance or Heat Effect. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Core body temperature increases in hot climates due to exercise workload, disrupting heat gain and loss of balance. The human thermoregulatory system regulates core body temperature through factors such as metabolic heat production, air temperature, humidity, and clothing. The study investigates physiological thermoregulatory responses in semiprofessional athletes during walking and jogging in different climatic conditions. Methods: A factorial experimental interventional design was used to evaluate different physical activity (low (L)=5 km/h and high (H)=8 km/h) and climatic conditions within the Thermal Environment Laboratory at Lund University, Sweden. The temperature within the climatic chamber was set at 40°C and 31°C, with a relative humidity of 20% and 70%, (hot dry (HD) and hot humid (HW), respectively, to account for a 28°C WBGT. The study used independent T-tests, ANOVA and simple linear regression models to analyse the physiological responses of semiprofessional athletes under different test conditions, comparing gender differences.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT07307391
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Heat Acclimation and Thermotolerance
Currently open trials in the same condition.
- NCT06670365 — Enhancing Heat Resiliency in Older Adults During Indoor Overheating Via Heat Acclimation by Warm Water Immersion · NA · recruiting
Other University of Valladolid trials
Trials by the same sponsor.
- NCT07302191 — High-Intensity Interval or Concurrent Exercise on Oxidative Stress and Inflammation in Obese Women · NA · completed
- NCT06696378 — Melatonin Supplementation and Exercise Program in Breast Cancer Women · NA · recruiting
- NCT06616181 — TDCS and Tele-rehabilitation Exercise in Fibromyalgia · NA · not yet recruiting
- NCT06326229 — Clinical Validation of Musculoskeletal ICF Core Set in Primary Care Physiotherapy · recruiting
- NCT06289439 — Effect of Green Tea Supplementation in Older Adult Women · NA · unknown
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07307391 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Valladolid
- Last refreshed: 31 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07307391.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing