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NCT05853523
The Desensitizing Treatment Effects of the Laser and Ozone on Dentin Hypersensitivity: In-vivo Comparison
Phase 2 trial testing Gas ozone in Dentin Sensitivity in 44 participants. Completed in 27 August 2022.
27 February 2022
Quick facts
| Lead sponsor | University of L'Aquila |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 44 |
| Start date | 27 February 2021 |
| Primary completion | 27 February 2022 |
| Estimated completion | 27 August 2022 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Gas ozone
- Diode laser and desensitized gel
Conditions studied
- Dentin Sensitivity — all drugs for Dentin Sensitivity →
Sponsor
University of L'Aquila
Who can join
Adults 18 to 70, any sex, with Dentin Sensitivity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this split mouth clinical trial is to compare clinical efficacy of diode laser and gas ozone in the treatment of dentine hypersensitivity (DHS) of non-carious-cervical lesion. The main questions it aims to answer are: * gas ozone affects dentine hypersensitivity? * diode laser affects dentine hypersensitivity? Participants, affected of DHS , were treated with gas ozone and diode laser.The pain severity was quantified according to the Visual Analogue Scale (VAS) before and after the treatmens.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Ozone and laser effects on dentin hypersensitivity treatment: a clinical study
D’Amario M, Carlo MD, Jahjah A, Mauro S, et al · · 2023 · DOI 10.21203/rs.3.rs-2942264/v1
Verify or expand the search:
- PubMed search for NCT05853523
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dentin Sensitivity
Currently open trials in the same condition.
- NCT06463938 — A Clinical Trial to Compare Lasotronix Alone or in Combination With CPP-ACP to Treat DH · NA · recruiting
Other University of L'Aquila trials
Trials by the same sponsor.
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- NCT05816213 — Point-of-care Low-field MRI in Acute Stroke · not yet recruiting
- NCT06958874 — Adjunctive Effect of Erythritol on Pocket Closure Rates · NA · recruiting
- NCT06790459 — Effects of the Ultra-low Frequencies TENS on the Arousal Circuits · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05853523 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of L'Aquila
- Last refreshed: 10 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05853523.
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