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NCT06958874
Adjunctive Effect of Erythritol on Pocket Closure Rates
NA trial testing Non-surgical periodontal therapy + sub-gingival air polishing in Periodontitis in 56 participants. Currently enrolling.
31 March 2025
Quick facts
| Lead sponsor | University of L'Aquila |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 56 |
| Start date | 8 November 2024 |
| Primary completion | 31 March 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Non-surgical periodontal therapy + sub-gingival air polishing
- Non-surgical periodontal therapy alone
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Pocket, Periodontal — all drugs for Pocket, Periodontal →
- Pocket, Gingival — all drugs for Pocket, Gingival →
Sponsor
University of L'Aquila
Who can join
35 and older, any sex, with Periodontitis or Pocket, Periodontal. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical trial is studying whether using erythritol powder during non-surgical periodontal treatment (deep cleaning) helps improve gum health in people with severe periodontitis. Participants with deep gum pockets (4 mm or more) receive standard treatment alone or standard treatment plus cleaning with erythritol powder. The goal is to evaluate if adding erythritol improves outcomes such as healing of gum pockets, bleeding, plaque levels, and gum attachment compared to standard treatment alone.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06958874
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06958874 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of L'Aquila
- Last refreshed: 6 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06958874.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing