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NCT05822895: COPILOT
Review of the Impact of a Computer-aided Real-time Polyp Detection System on Adult Colonoscopy
trial testing CADe enabled programme (GI Genius) in Colonic Polyp in 764 participants. Status unknown.
30 June 2025
Quick facts
| Lead sponsor | Sengkang General Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 764 |
| Start date | 2 January 2023 |
| Primary completion | 30 June 2025 |
| Estimated completion | 31 December 2025 |
| Sites | 1 location across Singapore |
Drugs / interventions tested
- CADe enabled programme (GI Genius)
Conditions studied
- Colonic Polyp — all drugs for Colonic Polyp →
Sponsor
Sengkang General Hospital
Who can join
Adults 21 to 90, any sex, with Colonic Polyp. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background: Removal of adenomatous polyps during colonoscopy is associated with long-term prevention of colorectal cancer-related deaths. Recently, there have been much interest in the use of artificial intelligence (AI) platforms to augment the routine endoscopic assessment of the colon to enhance adenoma detection rate (ADR). To date, computer assisted detection of polyps (CADe) have been shown to be safe, with a significant increase in ADR, without any concomitant increase in post-procedural complications. Aims: The investigators aim to evaluate the use of GI GeniusTM Intelligent Endoscopy Module in a multi-ethnic Asian population (Singapore) to increase in ADR and adenoma detected per colonoscopy (ADPC)to justify its effectiveness as an adjunct in polyp detection and training for colonoscopy. Methods: This study will be a single-institution cohort study, conducted over a 2-year period. Sengkang General Hospital (SKH) does an estimated 12,500 colonoscopies per year, with an average of 1,040 colonoscopies performed every month. Thus, given the case volume, the investigators expect to detect differences in ADR amongst endoscopists if any during this study period. As part of the subgroup analysis, the investigators also aim to compare the ADR rates of trainee endoscopists with and without the GI GeniusTM Intelligent Endoscopy Module to ascertain its utility as an education tool/training adjunct
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Real-World Assessment of the Efficacy of Computer-Assisted Diagnosis in Colonoscopy: A Single Institution Cohort Study in Singapore.
Koh GE, Ng B, Lagström RMB, Foo FJ, et al · · 2024 · cited 2× · PMID 40206538 · DOI 10.1016/j.mcpdig.2024.10.002
Verify or expand the search:
- PubMed search for NCT05822895
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colonic Polyp
Currently open trials in the same condition.
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- NCT07456111 — A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy · Phase 4 · recruiting
- NCT06483503 — Extra Wide Field of View Lens Study · active not recruiting
- NCT06077435 — Comparative Analysis of AI Software for Enhanced Polyp Detection and Diagnosis · NA · recruiting
Other Sengkang General Hospital trials
Trials by the same sponsor.
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- NCT07477561 — Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-I · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05822895 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sengkang General Hospital
- Last refreshed: 8 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05822895.
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