NCT05736185 is a NA clinical trial of PEEP selection in ARDS, Human, sponsored by Southeast University, China.

Who is sponsoring NCT05736185?

NCT05736185 is sponsored by Southeast University, China.

What drugs are being tested in NCT05736185?

Interventions in NCT05736185: PEEP selection.

What condition does NCT05736185 study?

NCT05736185 studies ARDS, Human.

Is NCT05736185 still recruiting?

NCT05736185 is currently completed. Last updated 4 June 2024.

Last reviewed 2024-06-04 · How we verify

NCT05736185

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Electric Impedance Tomography-Guided PEEP Titration

Completed NA Last updated 4 June 2024

What this trial tests

NA trial testing PEEP selection in ARDS, Human in 69 participants. Completed in 30 May 2024.

Timeline

25 February 2023

Primary endpoint
30 May 2024

30 May 2024

Quick facts

Lead sponsor	Southeast University, China
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	none
Primary purpose	other
Enrollment	69
Start date	25 February 2023
Primary completion	30 May 2024
Estimated completion	30 May 2024
Sites	1 location across China

Drugs / interventions tested

PEEP selection

Conditions studied

ARDS, Human — all drugs for ARDS, Human →

Sponsor

Southeast University, China

Who can join

18 and older, any sex, with ARDS, Human. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute respiratory syndrome distress (ARDS) is a clinical common syndrome with high mortality. Mechanical ventilation (MV) is the cornerstone of management of ARDS but can lead to ventilator-induced lung injury. Positive end-expiratory pressure (PEEP), as one of main component of MV, has been widely used in the clinical practice. However, how to best set PEEP is still a difficult problem for moderate to severe ARDS patients. EIT, an imaging tool evaluating the regional ventilation distribution at the bedside, can achieve the individual PEEP selection for all mechanically ventilated patients. This article compared the effect of PEEP titrated guided by EIT with fraction of inspired oxygen (FiO2)-PEEP table on the ventilation-perfusion mismatch.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for ARDS, Human

Currently open trials in the same condition.

NCT07070362 — Digital Early Warning System for Acute Lung Injury in Liver Surgery · recruiting
NCT06572280 — Non-invasive Phrenic Nerve Stimulation in ARDS Patient · NA · recruiting
NCT06119516 — Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study. · NA · recruiting
NCT06321497 — Extracorporeal Carbon Dioxide Removal Using PrismaLung in Reducing Ventilator Induced Lung Injury · recruiting
NCT06486259 — Regional Assessment of the Risk of Lung Injury in Ventilated Patients · recruiting

Other Southeast University, China trials

Trials by the same sponsor.

NCT07519512 — Effect of Early Transition to Assisted Ventilation on 28-day Successful Extubation in Critically Ill Patients · NA · recruiting
NCT06990477 — Effect of EIT-guided PEEP in ARDS Patients With Higher Recruitability · NA · recruiting
NCT07362537 — Enteral Nutrition Delivery in Prone Position Ventilated Patients With Moderate to Severe ARDS · NA · recruiting
NCT07327268 — Cyclic On-off Switching of Pulmonary Blood Flow in Moderate to Severe ARDS · not yet recruiting
NCT07284888 — Practices of Prone Positioning Ventilation in Patients With Moderate-to-Severe ARDS in Intensive Care Units: A Registry- · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05736185 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Southeast University, China
Last refreshed: 4 June 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05736185.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing