NCT05717881 is a NA clinical trial of Propolis in Insulin Resistance, sponsored by Aix Marseille Université.

Who is sponsoring NCT05717881?

NCT05717881 is sponsored by Aix Marseille Université.

What drugs are being tested in NCT05717881?

Interventions in NCT05717881: Propolis, Placebo.

What condition does NCT05717881 study?

NCT05717881 studies Insulin Resistance.

Is NCT05717881 still recruiting?

NCT05717881 is currently completed. Last updated 8 February 2023.

Last reviewed 2023-02-08 · How we verify

NCT05717881

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impact of Poplar Propolis on Metabolic Disturbances of Insulin Resistance

Completed NA Last updated 8 February 2023

What this trial tests

NA trial testing Propolis in Insulin Resistance in 9 participants. Completed in 10 September 2021.

Timeline

2 June 2020

Primary endpoint
30 September 2020

10 September 2021

Quick facts

Lead sponsor	Aix Marseille Université
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	triple
Primary purpose	prevention
Enrollment	9
Start date	2 June 2020
Primary completion	30 September 2020
Estimated completion	10 September 2021
Sites	1 location across France

Drugs / interventions tested

Propolis — full drug profile →
Placebo

Conditions studied

Insulin Resistance — all drugs for Insulin Resistance →

Sponsor

Aix Marseille Université

Who can join

Adults 18 to 60, any sex, with Insulin Resistance. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Propolis, a natural resinous mixture rich in polyphenols, produced by bees from a variety of plant sources, has shown significant therapeutic effects and may prevent the development of certain chronic diseases. Current evidence supports the beneficial effect of these bioactive phytochemicals on the management of type 2 diabetes mellitus (T2DM) and other chronic diseases. The objective of this study is to evaluate the effect of poplar propolis extract powder (PPEP) on glucose homeostasis and other clinical parameters in insulin-resistant patients (diagnosed by HOMA-IR index \> 1.85 for men and \> 2.07 for women).

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Poplar Propolis Improves Insulin Homeostasis in Non-Diabetic Insulin-Resistant Volunteers with Obesity: A Crossover Randomized Controlled Trial.
Sani L, Cardinault N, Astier J, Darmon P, et al · · 2023 · cited 11× · PMID 37627476 · DOI 10.3390/antiox12081481
Harnessing Nature's Toolbox: Naturally Derived Bioactive Compounds in Nanotechnology Enhanced Formulations.
Sanjai C, Gaonkar SL, Hakkimane SS. · · 2024 · cited 10× · PMID 39494011 · DOI 10.1021/acsomega.4c07756

Verify or expand the search:

Other trials of Propolis

Trials testing the same drug.

NCT07197073 — Antibacterial Effect of Ozonated Olive Oil, Propolis and Chlorhexidine Mouthwashes in Pediatric Patients · NA · completed
NCT06216262 — Evaluation of the Effectiveness of Home-Use Desensitizing Agents on Dentin Hypersensitivity · NA · completed
NCT05770297 — Effect of Propolis Administration for Dysmenorrhea in Endometriosis Patient With Levonorgestrel Implant Therapy · NA · unknown
NCT05569590 — Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching. · NA · completed
NCT04411758 — Propolis for Patients With Chronic Kidney Disease. · NA · completed

Other recruiting trials for Insulin Resistance

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07226128 — The Effects of Cognitive Behavioral Therapy on Insulin Resistance in People With HIV · NA · recruiting
NCT07505745 — MOTS-c for Improving Insulin Sensitivity in Adults With Prediabetes and Overweight/Obesity · Phase 2 · recruiting
NCT07220694 — Effects of Sabroxy® Supplementation on Insulin Resistance and Cognitive Function in Adults With Mild Cognitive Impairmen · NA · recruiting
NCT06768827 — New Mechanisms of Obesity · NA · recruiting

Other Aix Marseille Université trials

Trials by the same sponsor.

NCT05915130 — An Innovative Gait Training Program in Immersive Virtual Reality for Healthy Older Adults · NA · unknown
NCT06827106 — Dose-Quality Study in the Temporal Bone Computed Tomography in Routine Care · completed
NCT04504643 — Comparison of Three Motor-cognitive Training Programs · NA · completed
NCT04372225 — Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05717881 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Aix Marseille Université
Last refreshed: 8 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05717881.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing