NCT05700539

Internet-based Cognitive Behavioral Therapy for Adult Attention Deficit Hyperactivity Disorder

Recruiting now NA Last updated 2 September 2025

What this trial tests

NA trial testing Internet-based cognitive behavioral therapy in ADHD in 200 participants. Currently enrolling.

Timeline

25 January 2023

Primary endpoint
1 November 2025

31 December 2025

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	200
Start date	25 January 2023
Primary completion	1 November 2025
Estimated completion	31 December 2025
Sites	1 location across Sweden

Drugs / interventions tested

• Internet-based cognitive behavioral therapy

Conditions studied

• ADHD — all drugs for ADHD →

Sponsor

Karolinska Institutet

Who can join

18 and older, any sex, with ADHD. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Attention deficit hyperactivity disorder (ADHD) is a disorder characterized by lack of attention, hyperactivity, and impulsivity. It can have major impact on everyday life and result in negative consequences for one's personal, academic, and work situation. For individuals with symptoms of ADHD, increased levels of anxiety and depression are common, and an overall reduction of quality of life is often present. This study protocol describes a clinical trial of internet-based cognitive behavioral therapy (iCBT), using a randomized controlled study design, with the primary aim to increase quality of life, as well as to reduce symptoms of ADHD, anxiety, depression, and stress. A second aim is to investigate, by qualitative means, what aspects of treatment were perceived as helpful and hindering when it comes to completing iCBT. Two hundred participants with symptoms of ADHD will be included and randomized to two conditions (treatment and wait-list control). The treatment period is comprised of ten weeks, with two mandatory modules and ten modules from which the participants can choose freely. Self-report measures are completed by the participants at baseline and end of treatment, as well as at a six-month follow-up. The treatment is guided by therapists and consists of weekly correspondence with the participants. The study will utilize an intention to treat design, with ANOVAs and Reliable Change Index to evaluate treatment effects. The qualitative part of the project will be interview-based and employ thematic analysis. Lastly, a psychometric evaluation of a common instrument for determining ADHD-symptoms will also be made. The results will hopefully contribute to the evidence base for iCBT for individuals with symptoms of ADHD and help disseminate potentially effective interventions.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. A study protocol of a randomized controlled study of internet-based cognitive behavioral therapy for adult attention deficit hyperactivity disorder.
   Forsström D, Oscarsson M, Buhrman M, Rozental A. · · 2023 · PMID 37529408 · DOI 10.1016/j.invent.2023.100652