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NCT05693428
Influence of Anesthetics on Clinical Outcome During Cardiac Surgery in Adults
NA trial testing Propofol in CHD - Coronary Heart Disease in 90 participants. Completed in 26 November 2022.
19 November 2022
Quick facts
| Lead sponsor | Astana Medical University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | sequential |
| Masking | single |
| Primary purpose | supportive care |
| Enrollment | 90 |
| Start date | 22 January 2022 |
| Primary completion | 19 November 2022 |
| Estimated completion | 26 November 2022 |
| Sites | 1 location across Kazakhstan |
Drugs / interventions tested
- Propofol (Propofol) — full drug profile →
- Isoflurane (ISOFLURANE) — full drug profile →
- Sevoflurane — full drug profile →
Conditions studied
- CHD - Coronary Heart Disease — all drugs for CHD - Coronary Heart Disease →
Sponsor
Astana Medical University
Who can join
Adults 45 to 67, any sex, with CHD - Coronary Heart Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Abstract Cardiac surgery in adults is associated with the occurrence of post-operative complications. Even minor complications can increase the cost of their treatment. Given the potentially preventable nature of a number of these postoperative complications, preventive methods should be used to improve outcomes after cardiac surgery. One of them, is the choice of anaesthetic technique. Objectives: To evaluate the effects of sevoflurane, isoflurane and propofol on blood oxygen transport function and body energy expenditure during cardiac surgery in adults. Materials and methods. A total of 90 patients were included in the study. All patients were divided into 3 groups: 1- (n=30) included patients who were anesthetized with propofol. The second group (n=30) consisted of patients who underwent sevoflurane inhalation anaesthesia. Group 3 (n=30) was treated with isoflurane. All patients underwent coronary artery bypass grafting under cardiopulmonary bypass.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05693428
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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- NCT07269808 — Sedation During Endoscopy Using Remimazolam: Efficacy in a Novel Exploration · Phase 3 · recruiting
- NCT07460050 — Comparison of Two Sedative Agents in Terms of Controlled Hypotension · NA · not yet recruiting
- NCT07347496 — A Randomized, Controlled Clinical Trial Comparing Remimazolam Besylate Combined With Alfentanil Versus Propofol Combined · Phase 4 · not yet recruiting
Other Astana Medical University trials
Trials by the same sponsor.
- NCT07038213 — Study of Genome-associated Mechanisms of Diabetic Nephropathy and Evaluation of Nephroprotective Therapy in Patients Wit · enrolling by invitation
- NCT07517497 — The Course of Acute Respiratory Failure in Geriatric Patients With Hip Fracture Using Different Modes of a Vibroacoustic · NA · recruiting
- NCT05742789 — Effect of Anesthetics on Troponin I and С-reactive Protein · Phase 1 · completed
- NCT05143372 — Influence of Vibroacoustic Therapy Modes on the Course of Coronavirus Infection · NA · completed
- NCT05695287 — The Effects of Sevoflurane, Isoflurane and Propofol During Cardiac Surgery · Phase 1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05693428 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Astana Medical University
- Last refreshed: 23 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05693428.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing