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NCT05690074
Epidural Stimulation in Chronic Spinal Cord Injury Patients
NA trial testing Spectra Wave Writer™ Spinal Cord Stimulator System in Spinal Cord Injuries in 5 participants. Status unknown.
1 December 2025
Quick facts
| Lead sponsor | University Hospital, Motol |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 5 |
| Start date | 1 January 2023 |
| Primary completion | 1 December 2025 |
| Estimated completion | 30 December 2025 |
| Sites | 1 location across Czechia |
Drugs / interventions tested
- Spectra Wave Writer™ Spinal Cord Stimulator System
Conditions studied
- Spinal Cord Injuries — all drugs for Spinal Cord Injuries →
Sponsor
University Hospital, Motol
Who can join
Adults 18 to 60, any sex, with Spinal Cord Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Investigators propose to demonstrate that epidural stimulation (ES) can be used to recover significant levels of autonomic control of cardiovascular, urinary and sexual function as well as the ability to voluntarily control leg movements below the injury level. This intervention would provide an immediate therapeutic alternative to individuals who now have no recourse for treatment. In addition investigators suggest to prove on functional magnetic resonance imaging if there are some significant changes before and after the stimulation.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of epidural spinal cord stimulation in individuals with sensorimotor complete spinal cord injury: a pilot study.
Rybka V, Sediva K, Spackova L, Kolar P, et al · · 2025 · PMID 40673222 · DOI 10.3389/fnsys.2025.1622033
Verify or expand the search:
- PubMed search for NCT05690074
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Spinal Cord Injuries
Currently open trials in the same condition.
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- NCT07488793 — Remote Ischemic Conditioning for PwSCI · NA · recruiting
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Other University Hospital, Motol trials
Trials by the same sponsor.
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- NCT06868823 — Prospective Observational Pilot Study of LMWH Versus UFH as ECMO Anticoagulation in Lung Transplantation · recruiting
- NCT06102421 — Evaluation of the Effectiveness of Extracorporeal Shockwave Therapy in Patients With Patellar Tendinopathy on Its Microm · completed
- NCT07103317 — Comprehensive Coronary Physiology in Patients With Angina With Nonobstructive Coronary Arteries - Czech Republic · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05690074 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Motol
- Last refreshed: 16 March 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05690074.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing