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NCT07109804
Cuneiform Nucleus (CnF) Deep Brain Stimulation for Gait Facilitation Following Spinal Cord Injury
NA trial testing Deep Brain Stimulation (DBS) in Spinal Cord Injuries in 6 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | University of Miami |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | device feasibility |
| Enrollment | 6 |
| Start date | 30 April 2026 |
| Primary completion | 31 December 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Deep Brain Stimulation (DBS)
- Deep Brain Stimulation (DBS) Device Implant Procedure
- Training Sessions
Conditions studied
- Spinal Cord Injuries — all drugs for Spinal Cord Injuries →
Sponsor
University of Miami
Who can join
Adults 22 to 70, any sex, with Spinal Cord Injuries. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a study about deep brain stimulation (DBS) as an investigational treatment for walking impairment following spinal cord injury (SCI). The purpose of this study is to assess the feasibility and inform on the safety, and efficacy of CnF DBS to improve gait in SCI patients with incomplete injury who cannot effectively walk overground
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Stereotactic rodent-to-human approximation of the mesencephalic cuneiform nucleus to guide deep brain stimulation.
Hofer AS, Scheuber MI, Sartori AM, Skorup I, et al · · 2026 · PMID 41786287 · DOI 10.1016/j.brs.2026.103066
Verify or expand the search:
- PubMed search for NCT07109804
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Deep Brain Stimulation (DBS)
Trials testing the same drug.
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- NCT06542900 — Efficacy of Deep Brain Stimulation(DBS) for Treatment-Resistant Depression(TRD) · NA · not yet recruiting
- NCT06361004 — Exploring DBS Efficacy in Treatment-refractory Tourette's Syndrome · NA · not yet recruiting
- NCT05623306 — SEEG-Guided DBS for OCD · NA · recruiting
- NCT07526155 — Clinical Trial to Compare VIM vs PSA Bilateral Deep Brain Stimulation in Patients With Essential Tremor · NA · completed
Other recruiting trials for Spinal Cord Injuries
Currently open trials in the same condition.
- NCT07472985 — Protocol for Rapid Onset of Mobilization in Patients With Traumatic Spinal Cord Injury II (PROMPT-SCI II) Trial · NA · recruiting
- NCT07210411 — Acute and Chronic Repercussion of Spinal Cord Stimulation After Spinal Cord Injury · NA · recruiting
- NCT07488793 — Remote Ischemic Conditioning for PwSCI · NA · recruiting
- NCT07536386 — Self-balancing Personal Exoskeleton for SCI (WIP) · NA · recruiting
- NCT07210437 — Longitudinal Autonomic Characterization as a Predictor for Secondary Medical Complications Post-SCI · NA · recruiting
Other University of Miami trials
Trials by the same sponsor.
- NCT06003712 — Exploring the Effect of Mindfulness on Quality of Life (QoL) in Spinal Cord Injury (SCI) · NA · not yet recruiting
- NCT07322289 — Antibiotic-coated Braided Suture Study · NA · not yet recruiting
- NCT07472413 — Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot Project · Phase 3 · not yet recruiting
- NCT06077071 — MRIdian "RADAR" Trial · NA · not yet recruiting
- NCT07469592 — eHealth Mindfulness-based Music Therapy Intervention for Patients Undergoing Stem Cell Transplantation · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07109804 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Miami
- Last refreshed: 6 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07109804.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing