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NCT05662475
Effect of Periodontal Treatment on Visfatin, fetuin-a and Sirtuin 1 of Patients With Periodontitis and Type 2 Diabetes
NA trial testing GCF (gingival crevicular fluid) collection in Periodontal Diseases in 66 participants. Completed in 15 July 2022.
14 March 2022
Quick facts
| Lead sponsor | Ondokuz Mayıs University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 66 |
| Start date | 15 November 2021 |
| Primary completion | 14 March 2022 |
| Estimated completion | 15 July 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- GCF (gingival crevicular fluid) collection
- Non-surgical periodontal treatment completed in 24 hours
- HbA1c level determination in blood serum
Conditions studied
- Periodontal Diseases — all drugs for Periodontal Diseases →
- Type 2 Diabetes — all drugs for Type 2 Diabetes →
- Periodontitis — all drugs for Periodontitis →
Sponsor
Ondokuz Mayıs University
Who can join
Adults 31 to 81, any sex, with Periodontal Diseases or Type 2 Diabetes. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to determine the concentrations of Visfatin, Fetuin-A and Sirtuin 1 in the gingival crevicular fluid and clinical periodontal parameters in diabetic and systemically healthy individuals and to determine whether non-surgical periodontal treatment had any effect on these biomarkers and periodontal clinical parameters at the end of a 3-month follow-up period. The hypothesis of our study is that gingival crevicular fluid Visfatin, Fetuin-A and Sirtuin 1 concentrations will change with non-surgical periodontal treatment in type 2 diabetic and systemically healthy individuals and that this change will be associated with diabetes and clinical parameters.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05662475
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Periodontal Diseases
Currently open trials in the same condition.
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Other Ondokuz Mayıs University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05662475 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ondokuz Mayıs University
- Last refreshed: 22 December 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05662475.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing