Who is sponsoring NCT05562986?

NCT05562986 is sponsored by Ondokuz Mayıs University.

What drugs are being tested in NCT05562986?

Interventions in NCT05562986: GCF (gingival crevicular fluid) collection.

What condition does NCT05562986 study?

NCT05562986 studies Oral Hygiene, Orthodontics, Periodontal Diseases.

Is NCT05562986 still recruiting?

NCT05562986 is currently completed. Last updated 3 October 2022.

Last reviewed 2022-10-03 · How we verify

NCT05562986

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Impacts of Oral Irrigation in Orthodontic Patients

Completed NA Last updated 3 October 2022

What this trial tests

NA trial testing GCF (gingival crevicular fluid) collection in Oral Hygiene in 30 participants. Completed in 27 December 2018.

Timeline

1 March 2018

Primary endpoint
1 August 2018

27 December 2018

Quick facts

Lead sponsor	Ondokuz Mayıs University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	30
Start date	1 March 2018
Primary completion	1 August 2018
Estimated completion	27 December 2018
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

GCF (gingival crevicular fluid) collection

Conditions studied

Oral Hygiene — all drugs for Oral Hygiene →
Orthodontics — all drugs for Orthodontics →
Periodontal Diseases — all drugs for Periodontal Diseases →

Sponsor

Ondokuz Mayıs University

Who can join

12 and older, any sex, with Oral Hygiene or Orthodontics. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The present study aimed to investigate clinically the cleaning effectiveness of different treatment modalities, that is, oral irrigator or interdental brush usage addition to routine brushing and examine interleukin (IL)-1β, IL-10, matrix metalloproteinase (MMP)-1, MMP-8 levels in gingival crevicular fluid of orthodontic patients. The null hypothesis was that oral irrigators would be effective compared to interdental brush in the oral care of individuals who are orthodontic patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Human Randomized Controlled Trail Clinical and Biochemical Evaluation Oral Irrigator Effectiveness in Patients Under Orthodontic Treatment
Şahin E, Cetinkaya BO, Avci B, Kurt-Bayrakdar S, et al · · 2022 · cited 1× · DOI 10.21203/rs.3.rs-2256671/v1
Clinical and Biochemical Evaluation of Oral Irrigator Effectiveness in Fixed Orthodontic Treatment: A Randomised Clinical Trial.
Şahin E, Cetinkaya BO, Avci B, Kurt-Bayrakdar S, et al · · 2026 · PMID 42120952 · DOI 10.1111/idh.70087

Verify or expand the search:

Other trials of GCF (gingival crevicular fluid) collection

Trials testing the same drug.

NCT05662475 — Effect of Periodontal Treatment on Visfatin, fetuin-a and Sirtuin 1 of Patients With Periodontitis and Type 2 Diabetes · NA · completed

Other recruiting trials for Oral Hygiene

Currently open trials in the same condition.

NCT06848790 — Interdental Hygiene Methods in Young Adults · NA · recruiting
NCT07088666 — 0.2% Chlorhexidine vs MicroRepair ABX in Gingivitis · NA · recruiting
NCT06461611 — Effect of Health Diary on Self-management in Adolescent Patients With Fixed Orthodontic Appliance · NA · recruiting

Other Ondokuz Mayıs University trials

Trials by the same sponsor.

NCT07500389 — Postural Habits, Body Awareness, and Functional Performance Across BMI Categories in Women · not yet recruiting
NCT07535242 — Serum GFAP, NfL, VEGF and Clinical Progression in Progressive MS · not yet recruiting
NCT07504848 — Stroke Mobility and Caregiver Outcomes · not yet recruiting
NCT07525557 — Kinesiophobia, Pain and Disability in Chronic Neck Pain · recruiting
NCT07497802 — Mindfulness-Based Psychoeducation for Women With Gynecological Cancer · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05562986 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Ondokuz Mayıs University
Last refreshed: 3 October 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05562986.

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