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NCT05644418
EIT During FCV in the Intensive Care Unit
NA trial testing Flow Controlled Ventilation (FCV) in Post-cardiac Surgery in 10 participants. Completed in 9 May 2023.
9 May 2023
Quick facts
| Lead sponsor | Erasmus Medical Center |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | sequential |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 10 |
| Start date | 22 February 2022 |
| Primary completion | 9 May 2023 |
| Estimated completion | 9 May 2023 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Flow Controlled Ventilation (FCV)
Conditions studied
- Post-cardiac Surgery — all drugs for Post-cardiac Surgery →
Sponsor
Erasmus Medical Center
Who can join
18 and older, any sex, with Post-cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to study the effects of Flow Controlled Ventilation (FCV) following conventional mechanical ventilation (Pressure or Volume Controlled Ventilation) in postcardiac surgery ICU-patients to allow for future power calculations and to obtain experience with FCV. The main questions it aims to answer are: * What is the effect of FCV on the lung volume measured by Electrical Impedance Tomography (EIT)? * What is the effect of FCV on the minute volume? * What is the effect of FCV on the mechanical power and dissipated energy? Participants will be ventilated with PCV at baseline and then switched to FCV for 90 minutes while the lung volume, minute volume and mechanical power and dissipated energy levels are measured.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Flow-controlled ventilation decreases mechanical power in postoperative ICU patients.
Van Oosten JP, Francovich JE, Somhorst P, van der Zee P, et al · · 2024 · cited 13× · PMID 38502268 · DOI 10.1186/s40635-024-00616-9
Verify or expand the search:
- PubMed search for NCT05644418
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Post-cardiac Surgery
Currently open trials in the same condition.
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Other Erasmus Medical Center trials
Trials by the same sponsor.
- NCT07406269 — Clinical Evaluation of AI Decision Support for Early Rehabilitation After Surgery · NA · not yet recruiting
- NCT07402109 — CBCT Guided Markerless SBRT for Renal Cell Cancer · NA · recruiting
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- NCT07426575 — Evaluating the Usability of New Dialysis Bags · not yet recruiting
- NCT07329296 — The Regenerative Capacity of the Donor Liver After Living Donor Liver Transplantation: an Ambidirectional Cohort Study · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05644418 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Erasmus Medical Center
- Last refreshed: 12 January 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05644418.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing