NCT05547750 is a NA clinical trial of Vitamin K2 in Nocturnal Leg Cramps, sponsored by The Third People's Hospital of Chengdu.

Who is sponsoring NCT05547750?

NCT05547750 is sponsored by The Third People's Hospital of Chengdu.

What drugs are being tested in NCT05547750?

Interventions in NCT05547750: Vitamin K2, Placebo.

What condition does NCT05547750 study?

NCT05547750 studies Nocturnal Leg Cramps.

Is NCT05547750 still recruiting?

NCT05547750 is currently completed. Last updated 17 January 2025.

Last reviewed 2025-01-17 · How we verify

NCT05547750

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effect of Vitamin K2 in the Treatment of Nocturnal Leg Cramps in Older Population

Completed NA Last updated 17 January 2025

What this trial tests

NA trial testing Vitamin K2 in Nocturnal Leg Cramps in 200 participants. Completed in 31 December 2023.

Timeline

1 October 2022

Primary endpoint
31 December 2023

31 December 2023

Quick facts

Lead sponsor	The Third People's Hospital of Chengdu
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	200
Start date	1 October 2022
Primary completion	31 December 2023
Estimated completion	31 December 2023
Sites	1 location across China

Drugs / interventions tested

Vitamin K2 — full drug profile →
Placebo

Conditions studied

Nocturnal Leg Cramps — all drugs for Nocturnal Leg Cramps →

Sponsor

The Third People's Hospital of Chengdu

Who can join

65 and older, any sex, with Nocturnal Leg Cramps. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Nocturnal leg cramps (NLCs) are sudden contractions of the leg muscles, usually in the posterior calf muscles at night, affecting sleep quality. Because the precise pathophysiology of NCLs is unclear, different interventions have been proposed. There is conflicting evidence regarding the efficacy of conventional interventions in preventing cramps. Thus, the present study aims to investigate the effects of vitamin K2 for NLCs in a prospective randomized, double-blind, controlled trial.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial.
Tan J, Zhu R, Li Y, Wang L, et al · · 2024 · cited 8× · PMID 39466236 · DOI 10.1001/jamainternmed.2024.5726
Effect of vitamin K2 in the treatment of nocturnal leg cramps in the older population: Study protocol of a randomized, double-blind, controlled trial.
Li Y, Zhu R, Wang L, Tan J. · · 2023 · cited 1× · PMID 36908924 · DOI 10.3389/fnut.2023.1119233

Verify or expand the search:

Other trials of Vitamin K2

Trials testing the same drug.

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NCT05995522 — Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Ob · NA · completed
NCT05675163 — Antioxidant and Immune Effects of Vitamin K2 · NA · completed
NCT05161975 — Vitamin K2 Supplements for Muscle Recovery · NA · unknown
NCT04676958 — viTAmin K2 and rEcOVery From ExeRcise · NA · completed

Other The Third People's Hospital of Chengdu trials

Trials by the same sponsor.

NCT07321002 — PFLotus With the DePolar Mapping System in Patients With Persistent Atrial Fibrillation · NA · not yet recruiting
NCT07301190 — FIH Study of PFLotus in Persistent Atrial Fibrillation · NA · recruiting
NCT06811194 — PRIor Myocardial Infarction Identification on Electrocardiogram · enrolling by invitation
NCT06699368 — Clinical Study on the Risk of Left Atrial POP Ablation and Esophageal Injury Under Ultra-High Power and Related Influenc · NA · not yet recruiting
NCT06694610 — A Study on the Relationship Between Individualized Low Voltage Regions in Left Atrium and the Mechanism of Atrial Fibril · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05547750 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by The Third People's Hospital of Chengdu
Last refreshed: 17 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05547750.

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