NCT05537272 is a Phase 4 clinical trial of Tadalafil 5mg in Lower Urinary Tract Symptoms, sponsored by University Hospital of Split.

Who is sponsoring NCT05537272?

NCT05537272 is sponsored by University Hospital of Split.

What drugs are being tested in NCT05537272?

Interventions in NCT05537272: Tadalafil 5mg, Tamsulosin Hydrochloride 400 Microgram Prolonged-Release Oral Capsule, Placebo.

What condition does NCT05537272 study?

NCT05537272 studies Lower Urinary Tract Symptoms, Voiding Disorders, Pain, Quality of Life.

Is NCT05537272 still recruiting?

NCT05537272 is currently status unknown. Last updated 22 February 2023.

Last reviewed 2023-02-22 · How we verify

NCT05537272

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Efficacy of Tamsulosin and Tadalafil Compared to Placebo in the Treatment and Prevention of Urinary Disorders After Transperineal Prostate Biopsy

Status unknown Phase 4 Last updated 22 February 2023

What this trial tests

Phase 4 trial testing Tadalafil 5mg in Lower Urinary Tract Symptoms in 120 participants. Status unknown.

Timeline

1 September 2022

Primary endpoint
1 September 2023

1 September 2023

Quick facts

Lead sponsor	University Hospital of Split
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	prevention
Enrollment	120
Start date	1 September 2022
Primary completion	1 September 2023
Estimated completion	1 September 2023
Sites	1 location across Croatia

Drugs / interventions tested

Tadalafil 5mg — full drug profile →
Tamsulosin Hydrochloride 400 Microgram Prolonged-Release Oral Capsule — full drug profile →
Placebo

Conditions studied

Lower Urinary Tract Symptoms — all drugs for Lower Urinary Tract Symptoms →
Voiding Disorders — all drugs for Voiding Disorders →
Pain — all drugs for Pain →
Quality of Life — all drugs for Quality of Life →

Sponsor

University Hospital of Split

Who can join

Eligibility, male only, with Lower Urinary Tract Symptoms or Voiding Disorders. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluate the therapeutic efficacy of tamsulosin and tadalafil compared to placebo in the treatment and prevention of urinary disorders after transperineal prostate biopsy

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Tadalafil 5mg

Trials testing the same drug.

NCT06543628 — Evaluation of Tadalafil Combined With LIPUS for Treating Erectile Dysfunction · NA · completed
NCT06583590 — Evaluation of Efficacy of Botulinum Toxin A Plus Oral Tadalafil 5 mg in Diabetic Men With Erectile Dysfunction · Phase 2, PHASE3 · recruiting
NCT05558007 — Safety and Efficacy Evaluation of BZ371A Topically Applied on Prostatectomized Patients · Phase 2 · recruiting
NCT07499804 — Effect of Tadalafil on Endometrial Thickness and Frozen Embryo Transfer Outcomes · Phase 4 · recruiting
NCT06809205 — Efficacy and Safety of Tadalafil, Tamsulosin, and Their Combinations in Treating Lower Urinary Tract Symptoms in BPH Pat · Phase 4 · completed

Other recruiting trials for Lower Urinary Tract Symptoms

Currently open trials in the same condition.

NCT06481436 — Use of Artificial Intelligence by Urogynecologic Patients · NA · active not recruiting
NCT06351683 — Testing MitoQ on Lower Urinary Tract Symptoms in Older Women With Metabolic Syndrome · Phase 2 · recruiting
NCT06225479 — PRescription Exercise for Older Men With Urinary Disease · NA · recruiting
NCT06179654 — Preoperative Pelvic Floor Physical Therapy to Minimize Stress Urinary Incontinence After Holmium Laser Enucleation of th · NA · recruiting
NCT06070675 — Comparison of a Paper and Automated Bladder Diary in Pediatric Patients · NA · recruiting

Other University Hospital of Split trials

Trials by the same sponsor.

NCT07130006 — Preoperative Use of Peripheral Nerve Blocks in Elderly Patients With Hip Fractures · Phase 4 · not yet recruiting
NCT06595329 — Comparison Between Epidural Analgesia and Intrathecal Opioid Analgesia for Pain Management in Open Nephrectomy · Phase 1 · recruiting
NCT06399445 — Measurement of Blood Loss in Adenotonsillectomy During General Anesthesia According to the Application of Nondepolarizin · Phase 4 · recruiting
NCT06051825 — Diagnostic Importance of the C-reactive Protein From Blood and Saliva in Children With Acute Appendicitis · unknown
NCT05202600 — Justification of Incidental Appendectomy With Respect to Pathohistological Findings · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05537272 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital of Split
Last refreshed: 22 February 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05537272.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing