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NCT05465980
Development and Validation of the Prediction Model for Cognitive Impairment
trial in Stroke, Acute in 496 participants. Status unknown.
31 December 2023
Quick facts
| Lead sponsor | Shenzhen Second People's Hospital |
|---|---|
| Status | Status unknown |
| Study type | OBSERVATIONAL |
| Enrollment | 496 |
| Start date | 1 September 2022 |
| Primary completion | 31 December 2023 |
| Estimated completion | 30 September 2024 |
Conditions studied
- Stroke, Acute — all drugs for Stroke, Acute →
Sponsor
Shenzhen Second People's Hospital
Who can join
60 and older, any sex, with Stroke, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
According to the "Chinese Stroke Report" released in 2020, the incidence of stroke in China is 1114.8/100,000, acute ischemic stroke (AIS) accounts for 70% to 80% of the total number of stroke population, and elderly stroke patients are up to 2/3. About 1/3 of stroke patients would experience post-stroke cognitive impairment (PSCI), which seriously affected patients' quality of life and survival time, and increases disease and economic burden. Therefore, early identification, assessment, prevention and intervention of PSCI, and improvement of patients' quality of life and prognosis have become the focus of clinical research. This is a prospective cohort study. We intend to: (1) continuously collect elderly AIS patients who will be admitted to the Department of Neurology, The Department of Rehabilitation and the Department of Gerontology of Shenzhen Second People's Hospital from 2022 year to 2024 year; (2) collect baseline and follow-up data, and build a prediction model for cognitive impairment in elderly AIS patients; (3) internal validation using Bootstrap model; (4) collect the data of the elderly AIS patients who will be admitted to Shenzhen Longhua District People's Hospital andShenzhen Longgang Central Hospital, and conduct external validation; (5) evaluate the predictive efficacy of the model.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Nonlinear relationship between triglycerides and cognitive function after acute ischemic stroke among older adults.
Cao S, Teng L, Gao M, Hu S, et al · · 2024 · cited 3× · PMID 38524625 · DOI 10.1016/j.heliyon.2024.e27943
Verify or expand the search:
- PubMed search for NCT05465980
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05465980 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shenzhen Second People's Hospital
- Last refreshed: 20 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05465980.
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