Last reviewed · How we verify

NCT05465980

Development and Validation of the Prediction Model for Cognitive Impairment

Status unknown Last updated 20 July 2022
What this trial tests

trial in Stroke, Acute in 496 participants. Status unknown.

Timeline
1 September 2022
Primary endpoint
31 December 2023
30 September 2024

Quick facts

Lead sponsorShenzhen Second People's Hospital
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment496
Start date1 September 2022
Primary completion31 December 2023
Estimated completion30 September 2024

Conditions studied

Sponsor

Shenzhen Second People's Hospital

Who can join

60 and older, any sex, with Stroke, Acute. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

According to the "Chinese Stroke Report" released in 2020, the incidence of stroke in China is 1114.8/100,000, acute ischemic stroke (AIS) accounts for 70% to 80% of the total number of stroke population, and elderly stroke patients are up to 2/3. About 1/3 of stroke patients would experience post-stroke cognitive impairment (PSCI), which seriously affected patients' quality of life and survival time, and increases disease and economic burden. Therefore, early identification, assessment, prevention and intervention of PSCI, and improvement of patients' quality of life and prognosis have become the focus of clinical research. This is a prospective cohort study. We intend to: (1) continuously collect elderly AIS patients who will be admitted to the Department of Neurology, The Department of Rehabilitation and the Department of Gerontology of Shenzhen Second People's Hospital from 2022 year to 2024 year; (2) collect baseline and follow-up data, and build a prediction model for cognitive impairment in elderly AIS patients; (3) internal validation using Bootstrap model; (4) collect the data of the elderly AIS patients who will be admitted to Shenzhen Longhua District People's Hospital andShenzhen Longgang Central Hospital, and conduct external validation; (5) evaluate the predictive efficacy of the model.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Nonlinear relationship between triglycerides and cognitive function after acute ischemic stroke among older adults.
    Cao S, Teng L, Gao M, Hu S, et al · · 2024 · cited 3× · PMID 38524625 · DOI 10.1016/j.heliyon.2024.e27943

Verify or expand the search:

Other recruiting trials for Stroke, Acute

Currently open trials in the same condition.

Other Shenzhen Second People's Hospital trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05465980.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing