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NCT07253870
Comperative Effects of Transcutaneous Auricular and Cervical Vagus Nerve Stimulation in Subacute Stroke Patients
NA trial testing Transcutaneous vagus nerve stimulation through auricular branch along with task specific exercises in Stroke in 54 participants. Currently enrolling.
20 May 2026
Quick facts
| Lead sponsor | Lahore University of Biological and Applied Sciences |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 20 November 2025 |
| Primary completion | 20 May 2026 |
| Estimated completion | 20 May 2026 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Transcutaneous vagus nerve stimulation through auricular branch along with task specific exercises
- Transcutaneous vagus nerve stimulation through cervical branch along with task specific exercises
Conditions studied
- Stroke — all drugs for Stroke →
- Stroke, Acute — all drugs for Stroke, Acute →
Sponsor
Lahore University of Biological and Applied Sciences
Who can join
Adults 45 to 70, any sex, with Stroke or Stroke, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to determine whether transcutaneous vagus nerve stimulation (tVNS) via auricular or cervical branches enhances recovery when combined with task-specific training in subacute stroke patients. We anticipate finding that both stimulation methods may improve upper limb motor function compared to conventional therapy. The research is expected to reveal specific cognitive domains (attention, memory, executive function) that benefit most from each stimulation approach, while also demonstrating meaningful improvements in patients' quality of life measures. These findings may make a significant practical contribution by providing clinicians with evidence-based guidance on suitable tVNS approach for improving functional independence and quality of life for stroke survivors.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07253870
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Lahore University of Biological and Applied Sciences trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07253870 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lahore University of Biological and Applied Sciences
- Last refreshed: 3 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07253870.
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