Last reviewed · How we verify
NCT07425197: DNS CSE SIJD
Comparative Effects of Two Rehabilitation Approaches on Lumbopelvic Function in Sacroiliac Joint Dysfunction
NA trial testing Dynamic Neuromuscular Stabilization in Sacroiliac Joint Dysfunction in 40 participants. Not yet recruiting.
18 March 2026
Quick facts
| Lead sponsor | Lahore University of Biological and Applied Sciences |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 18 March 2026 |
| Primary completion | 18 March 2026 |
| Estimated completion | 27 September 2026 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Dynamic Neuromuscular Stabilization
- Core stabilization Exercise Program
Conditions studied
- Sacroiliac Joint Dysfunction — all drugs for Sacroiliac Joint Dysfunction →
Sponsor
Lahore University of Biological and Applied Sciences
Who can join
Adults 30 to 45, any sex, with Sacroiliac Joint Dysfunction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This research compares two rehabilitation strategies for people with sacroiliac joint dysfunction (SIJD): Dynamic Neuromuscular Stabilization (DNS) and Core Stability Exercises (CSE). SIJD is presented as a biomechanical source of low-back, buttock and leg pain caused by altered joint mechanics, muscle control problems, or asymmetric pelvic alignment; diagnosis relies on clinical provocation tests and exclusion of other causes. The study aims to determine which of the two exercise-based approaches better reduces pain and improves lumbopelvic control. The trial is a single-blinded, parallel randomized controlled trial conducted in an outpatient physiotherapy setting with supervised sessions over four weeks. Adults aged 20-50 with at least three positive SIJ provocation tests and moderate, chronic pain were included; important exclusions were prior spinal/pelvic surgery, systemic inflammatory disease, pregnancy, cardiopulmonary limitation or poor session attendance. Each participant received a baseline conventional physiotherapy package; one arm received a DNS program (breathing-based and developmental movement patterns) and the other performed progressive core-stability training emphasizing transversus abdominis and multifidus activation. Primary outcomes are pain (Numeric Pain Rating Scale) and lumbopelvic stability measured with a pressure biofeedback unit (PBU). Data were collected at baseline and after four weeks; the analysis plan uses SPSS with paired and independent t-tests, ANCOVA to adjust for baseline differences, and effect sizes/confidence intervals to interpret clinical relevance. Safety, informed consent, assessor blinding and standard ethical safeguards are described. The synopsis notes a gap in direct RCT evidence comparing DNS and CSE for SIJD and positions this trial to address that gap with clinical and mechanistic outcomes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07425197
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dynamic Neuromuscular Stabilization
Trials testing the same drug.
- NCT07386119 — Investigation of the Effects of Vestibular Rehabilitation and Dynamic Neuromuscular · NA · active not recruiting
- NCT06239753 — The Impact of Dynamic Neuromuscular Stabilization on Pregnancy · NA · recruiting
- NCT06277700 — Effects of Dynamic Stabilizatıon Exercises and HVLA Manipulatıon in Low Back Paın · NA · completed
Other recruiting trials for Sacroiliac Joint Dysfunction
Currently open trials in the same condition.
- NCT07310368 — Comparison of the Effectiveness of Mobilization and Myofascial Release Techniques in Patients With Sacroiliac Joint Dysf · NA · recruiting
- NCT07229287 — Kinetic Control Exercises to Reduce Pain and Improve Balance, Walking, and Stamina in Sacroiliac Joint Issues · NA · recruiting
- NCT07037173 — Effect of K-Taping and Yoga Therapy in Postural Correction for Sacroiliac Jointamong Weightlifters · NA · active not recruiting
- NCT06487936 — Real-World Registry Study on Patient Satisfaction With TransLoc 3D SI Joint Fusion · recruiting
- NCT06690463 — Comparison of Diagnostic and Therapeutic Efficacy of Periarticular and/or Intraarticular Lidocaine Injections Under Ultr · NA · active not recruiting
Other Lahore University of Biological and Applied Sciences trials
Trials by the same sponsor.
- NCT07529093 — Combined Effects of Mulligan's Mobilization With Movement and Kinetic Control Training on Pain, Range of Motion, Gait an · NA · not yet recruiting
- NCT07474818 — Loaded and Task Specific Training in Spastic Diaplegic CP to Improve Gait and Functional Mobility. · NA · not yet recruiting
- NCT07401706 — Effects of Vestibular Rehabilitation and Routine Physical Therapy in Athletes With Post Concussion Syndrome · NA · not yet recruiting
- NCT07460011 — Effects of Pain Neuroscience Education on Pain, Kinesiophobia in Patients With Non Specific Low Back Pain · NA · not yet recruiting
- NCT07395154 — Comparison of Integrated Neuromuscular Inhibition Technique (INIT) and Active Release Technique (ART) in Patients With U · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07425197 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lahore University of Biological and Applied Sciences
- Last refreshed: 19 March 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07425197.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing