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NCT05437588
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
NA trial testing Genetic testing in Major Depressive Disorder in 240 participants. Currently enrolling.
29 June 2027
Quick facts
| Lead sponsor | University of Alabama at Birmingham |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 240 |
| Start date | 1 October 2022 |
| Primary completion | 29 June 2027 |
| Estimated completion | 30 June 2027 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Genetic testing
Conditions studied
- Major Depressive Disorder — all drugs for Major Depressive Disorder →
- Suicidal Ideas — all drugs for Suicidal Ideas →
- Suicide, Attempted — all drugs for Suicide, Attempted →
- MDD — all drugs for MDD →
Sponsor
University of Alabama at Birmingham
Who can join
Adults 10 to 24, any sex, with Major Depressive Disorder or Suicidal Ideas. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future. This research is also to test the effects of standard treatment of depression on improvement in depressive and suicidal behavior and on biomarkers (e.g. miRNA) for these disorders.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05437588
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other University of Alabama at Birmingham trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05437588 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Alabama at Birmingham
- Last refreshed: 11 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05437588.
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