Last reviewed · How we verify
NCT05388526
Frailty and Cognitive Function in Parkinson's Disease.
trial testing No intervention in Parkinson Disease in 100 participants. Completed in 30 June 2023.
31 May 2023
Quick facts
| Lead sponsor | University of Oviedo |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 25 May 2022 |
| Primary completion | 31 May 2023 |
| Estimated completion | 30 June 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- No intervention
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
University of Oviedo
Who can join
Eligibility, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Introduction: Parkinson's disease (PD) is the association of tremor, rigidity, akinesia-bradykinesia and loss of postural reflexes. Non-motor symptoms such as cognitive impairment may also develop. Cognitive impairment can be highly variable in its progression, symptoms and severity and can begin from the onset of the disease to the most advanced stages. Frailty is a syndrome characterized by a decrease in physiological reserve that results in an individual's increased vulnerability, which can lead to a variety of adverse factors when exposed to stressors. PD and frailty are highly prevalent in older people and are associated with increased morbidity and mortality. The presence of frailty in patients with PD is poorly studied, as is the association between cognitive impairment and frailty in this patient profile. Objective: Evaluate the relationship between frailty and cognitive impairment in patients with PD or secondary parkinsonism. Study design: observational, descriptive, correlative and cross-sectional. Study population: The subjects that will be part of this study will be men and women with a diagnosis of PD or secondary parkinsonism belonging to the Health Area V of the Health Service of the Principality of Asturias, Spain.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Associations between frailty and cognitive impairment in Parkinson´s disease: a cross-sectional study.
Sousa-Fraguas MC, Rodríguez-Fuentes G, Lastra-Barreira D, Conejo NM. · · 2025 · cited 4× · PMID 39751989 · DOI 10.1007/s40520-024-02922-4
Verify or expand the search:
- PubMed search for NCT05388526
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05388526 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Oviedo
- Last refreshed: 21 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05388526.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing