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NCT05388526

Frailty and Cognitive Function in Parkinson's Disease.

Completed Last updated 21 December 2023
What this trial tests

trial testing No intervention in Parkinson Disease in 100 participants. Completed in 30 June 2023.

Timeline
25 May 2022
Primary endpoint
31 May 2023
30 June 2023

Quick facts

Lead sponsorUniversity of Oviedo
StatusCompleted
Study typeOBSERVATIONAL
Enrollment100
Start date25 May 2022
Primary completion31 May 2023
Estimated completion30 June 2023
Sites1 location across Spain

Drugs / interventions tested

Conditions studied

Sponsor

University of Oviedo

Who can join

Eligibility, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Introduction: Parkinson's disease (PD) is the association of tremor, rigidity, akinesia-bradykinesia and loss of postural reflexes. Non-motor symptoms such as cognitive impairment may also develop. Cognitive impairment can be highly variable in its progression, symptoms and severity and can begin from the onset of the disease to the most advanced stages. Frailty is a syndrome characterized by a decrease in physiological reserve that results in an individual's increased vulnerability, which can lead to a variety of adverse factors when exposed to stressors. PD and frailty are highly prevalent in older people and are associated with increased morbidity and mortality. The presence of frailty in patients with PD is poorly studied, as is the association between cognitive impairment and frailty in this patient profile. Objective: Evaluate the relationship between frailty and cognitive impairment in patients with PD or secondary parkinsonism. Study design: observational, descriptive, correlative and cross-sectional. Study population: The subjects that will be part of this study will be men and women with a diagnosis of PD or secondary parkinsonism belonging to the Health Area V of the Health Service of the Principality of Asturias, Spain.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Associations between frailty and cognitive impairment in Parkinson´s disease: a cross-sectional study.
    Sousa-Fraguas MC, Rodríguez-Fuentes G, Lastra-Barreira D, Conejo NM. · · 2025 · cited 4× · PMID 39751989 · DOI 10.1007/s40520-024-02922-4

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Other trials of No intervention

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