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NCT05378490: ASIST-1
The Akershus Study of Ischemic Stroke and Thrombolysis -1
trial in Stroke, Acute in 6,000 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | University Hospital, Akershus |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 6,000 |
| Start date | 1 January 2012 |
| Primary completion | 31 December 2025 |
| Estimated completion | 31 December 2040 |
| Sites | 1 location across Norway |
Conditions studied
- Stroke, Acute — all drugs for Stroke, Acute →
- Intracerebral Hemorrhage — all drugs for Intracerebral Hemorrhage →
- Stroke, Ischemic — all drugs for Stroke, Ischemic →
- TIA — all drugs for TIA →
Sponsor
University Hospital, Akershus
Who can join
18 and older, any sex, with Stroke, Acute or Intracerebral Hemorrhage. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This observational study comprises consecutively patients with cerebrovascular diseases admitted to the Stroke Unit at Akershus University Hospital in Norway. Akershus University Hospital is the largest emergency care hospital in Norway and has a catchment area covering a population of 550.000, which is approximately 10 % of the Norwegian population and reasonably representative according to data from Statistics Norway. The hospital is public and serving both as a primary hospital and a university hospital. Due to the Norwegian, national, all-covering health-insurance, all patients enter the hospital and are considered for further in-patient care on the same conditions. The hospital has a stroke unit classified as a comprehensive stroke center according to European Stroke Organisation standards. Acute stroke management follows national and international guidelines. Overall, the ASIST-1 study will investigate management, outcome and prognosis of stroke and stroke care pathways and later follow up in primary care using several approaches combining existing clinical data from a representative population with different Norwegian health registries. Parts of the study are retrospective with prospective follow-up by health registries and parts of the study are prospective.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Impact of white matter lesions on associations between prehospital blood pressure and outcomes in spontaneous intracerebral hemorrhage.
Larsen KT, Holt Jahr S, Nordahl Selseth M, Lied-Herland T, et al · · 2025 · PMID 40501043 · DOI 10.1177/23969873251343495
Verify or expand the search:
- PubMed search for NCT05378490
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other University Hospital, Akershus trials
Trials by the same sponsor.
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- NCT06731985 — The Follow-up After Shorter Tapes Study. Effectiveness and Safety of Shorter Trans-obturator Tapes. · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05378490 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Akershus
- Last refreshed: 5 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05378490.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing