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NCT05231941
Comparison of Intraoperative Intravenous Lidocaine Infusion and Transversus Abdominis Plane (TAP) Block for Post-operative Analgesia Following Laproscopic Cholecystectomy
NA trial testing Lidocaine IV in Post Operative Pain in 90 participants. Completed in 17 October 2022.
17 October 2022
Quick facts
| Lead sponsor | Aga Khan University Hospital, Pakistan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 25 February 2022 |
| Primary completion | 17 October 2022 |
| Estimated completion | 17 October 2022 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Lidocaine IV — full drug profile →
- Ropivacaine (ROPIVACAINE) — full drug profile →
Conditions studied
- Post Operative Pain — all drugs for Post Operative Pain →
Sponsor
Aga Khan University Hospital, Pakistan
Who can join
Adults 18 to 65, any sex, with Post Operative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is aimed to determine the post operative pain after laparoscopic cholecystectomy by dividing patients into three different group. Group A will receive lidocaine 2mg/kg bolus at induction followed by 1.5mg/kg/hr infusion. Group B will receive bilateral subcostal TAP block with 0.375% 20ml Ropivicaine on each side. Group C will not receive any additional pain regime apart from the routine intraoperative analgesics. Pain score will be assessed post operatively for 24 hours at regular intervals using visual analog score.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Comparison of intraoperative intravenous lidocaine infusion and transversus abdominis plane block for postoperative analgesia following laparoscopic cholecystectomy: a randomized controlled trial.
Sheikh H, Zafar S, Nawaz K, Ullah H. · · 2025 · PMID 40400189 · DOI 10.17085/apm.24159
Verify or expand the search:
- PubMed search for NCT05231941
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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- NCT06433713 — Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Section · Phase 2 · completed
Other recruiting trials for Post Operative Pain
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05231941 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aga Khan University Hospital, Pakistan
- Last refreshed: 26 June 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05231941.
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