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NCT06243120
Intravenous Lidocaine for Treating Intrathecal Fentanyl Induced Pruritus
EARLY_PHASE1 trial testing Lidocaine IV in Pruritus Caused by Drug in 54 participants. Status unknown.
1 September 2024
Quick facts
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 54 |
| Start date | 1 March 2024 |
| Primary completion | 1 September 2024 |
| Estimated completion | 1 October 2024 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Lidocaine IV — full drug profile →
Conditions studied
- Pruritus Caused by Drug — all drugs for Pruritus Caused by Drug →
Sponsor
Ain Shams University
Who can join
Adults 18 to 70, any sex, with Pruritus Caused by Drug. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study will assess efficacy of intravenous lidocaine 1 mg/kg diluted with 0.9% sodium chloride to a volume of 100 ml to suppress intrathecal fentanyl induced pruritus. This will be compared to control group who will receive 100 ml normal saline as placebo. The main outcome is regression of initial VAS score with incidence of pruritus.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06243120
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Lidocaine IV
Trials testing the same drug.
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- NCT06433713 — Effect of Intraoperative Intravenous Lidocaine on Postoperative Pain and Return of Bowel Function After Cesarean Section · Phase 2 · completed
- NCT06457100 — Esmolol Versus Lidocaine on the Quality of Postoperative Recovery in Patients Undergoing Functional Endoscopic Sinus Sur · Phase 1, PHASE2 · active not recruiting
Other recruiting trials for Pruritus Caused by Drug
Currently open trials in the same condition.
- NCT07054775 — Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section · Phase 4 · recruiting
- NCT06297499 — Ondansetron Use for Preventing Pruritus in Patients Undergoing Cesarean Section · Phase 1 · recruiting
Other Ain Shams University trials
Trials by the same sponsor.
- NCT07435493 — Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstru · NA · not yet recruiting
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
- NCT07531030 — Posterior Pericapsular Deep Gluteal Block Combined With Pericapsular Nerve Group and Lateral Femoral Cutaneous Nerve Blo · NA · not yet recruiting
- NCT06839027 — Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass · not yet recruiting
- NCT07516535 — DISS vs FANS in Suction-Assisted RIRS for Medium-Sized Renal Stones · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06243120 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ain Shams University
- Last refreshed: 6 February 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06243120.
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