Last reviewed · How we verify
NCT05150093
Deep Brain Stimulation in Laryngeal Dystonia and Voice Tremor
NA trial testing Deep Brain Stimulation in Laryngeal Dystonia in 120 participants. Currently enrolling.
31 August 2027
Quick facts
| Lead sponsor | Massachusetts Eye and Ear Infirmary |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 120 |
| Start date | 21 June 2022 |
| Primary completion | 31 August 2027 |
| Estimated completion | 31 August 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Deep Brain Stimulation
Conditions studied
- Laryngeal Dystonia — all drugs for Laryngeal Dystonia →
- Spasmodic Dysphonia — all drugs for Spasmodic Dysphonia →
- Tremor — all drugs for Tremor →
- Dystonia — all drugs for Dystonia →
Sponsor
Massachusetts Eye and Ear Infirmary — full company profile →
Who can join
Adults 18 to 80, any sex, with Laryngeal Dystonia or Spasmodic Dysphonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goals of this project are 1) to determine the incidence of neurological voice disorders in patients with dystonia and essential tremor undergoing deep brain stimulation (DBS), 2) investigate the neuroimaging and intracranial neurophysiology correlates of voice dysfunction in these subjects, and subsequently 3) determine the effects of DBS on voice function.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Deep Brain Stimulation for the Management of Refractory Neurological Disorders: A Comprehensive Review.
Rissardo JP, Vora NM, Tariq I, Mujtaba A, et al · · 2023 · cited 17× · PMID 38004040 · DOI 10.3390/medicina59111991
Verify or expand the search:
- PubMed search for NCT05150093
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Laryngeal Dystonia
Currently open trials in the same condition.
- NCT07443891 — Brain Network Changes After Vibro-tactile Stimulation in Laryngeal Dystonia · NA · recruiting
- NCT05150106 — Characterization of Clinical Phenotypes of Laryngeal Dystonia and Voice Tremor · recruiting
- NCT05506085 — Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application · recruiting
- NCT04421365 — Brain-Computer Interfaces in Laryngeal Dystonia · NA · recruiting
- NCT05216770 — Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor · EARLY_PHASE1 · recruiting
Other Massachusetts Eye and Ear Infirmary trials
Trials by the same sponsor.
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- NCT06688578 — Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait · NA · recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05150093 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Massachusetts Eye and Ear Infirmary
- Last refreshed: 2 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05150093.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing