Last reviewed · How we verify
NCT05129098
Left Bundle Branch Pacing Versus Conventional Pacing in Atrioventricular Block
NA trial testing Left bundle branch pacing lead (Select Secure 3830 lead) in Atrioventricular Nodal Disease in 38 participants. Completed in 20 December 2022.
20 December 2022
Quick facts
| Lead sponsor | University Hospital of Patras |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 38 |
| Start date | 13 July 2021 |
| Primary completion | 20 December 2022 |
| Estimated completion | 20 December 2022 |
| Sites | 1 location across Greece |
Drugs / interventions tested
- Left bundle branch pacing lead (Select Secure 3830 lead)
- Right ventricular active fixation lead
Conditions studied
- Atrioventricular Nodal Disease — all drugs for Atrioventricular Nodal Disease →
Sponsor
University Hospital of Patras
Who can join
Adults 18 to 90, any sex, with Atrioventricular Nodal Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recently, the concept of physiological pacing has emerged in the clinical practice, in an attempt to prevent the deteriorating effects of right ventricular pacing in the long-term. Left bundle branch pacing seems to be a safe procedure with promising results that may prevent intraventricular dyssynchony compared with the conventional right ventricular pacing.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Safety and efficacy of left bundle branch area pacing compared with right ventricular pacing in patients with bradyarrhythmia and conduction system disorders: a systematic review and meta-analysis
Leventopoulos G, Travlos CK, Aronis KN, Anagnostopoulou V, et al · · 2023 · DOI 10.1101/2023.02.09.23285675
Verify or expand the search:
- PubMed search for NCT05129098
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atrioventricular Nodal Disease
Currently open trials in the same condition.
- NCT06324682 — ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing · recruiting
Other University Hospital of Patras trials
Trials by the same sponsor.
- NCT07250529 — Left Bundle Branch Pacing vs Right Ventricular Pacing on AHRE Burden in Patients With Preserved LVEF · NA · recruiting
- NCT07305194 — Study of AHRE Burden in Patients Undergoing Bachmann Bundle Area Pacing and Left Bundle Branch Pacing. · not yet recruiting
- NCT06942260 — Vascular Access Registry · recruiting
- NCT05605288 — Distal Versus Conventional Transradial Artery Access for Coronary Catheterization in Patients With STEMI · NA · recruiting
- NCT06689111 — Correlation of Typical LBBB Mechanical Activation Pattern by 2D Strain Echocardiography With Acute GWE Improvement in Pa · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05129098 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital of Patras
- Last refreshed: 27 October 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05129098.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing