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NCT05110690
Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
NA trial testing Behavioral Activation in Older Adults in 24 participants. Completed in 22 December 2022.
22 December 2022
Quick facts
| Lead sponsor | Washington University School of Medicine |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 24 |
| Start date | 17 November 2021 |
| Primary completion | 22 December 2022 |
| Estimated completion | 22 December 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Behavioral Activation
- Medication Optimization — full drug profile →
Conditions studied
- Older Adults — all drugs for Older Adults →
- Anxiety — all drugs for Anxiety →
- Depression — all drugs for Depression →
- Cardiac Surgery — all drugs for Cardiac Surgery →
Sponsor
Washington University School of Medicine
Who can join
60 and older, any sex, with Older Adults or Anxiety. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Inadequate management of preoperative mental health disorders often contributes to poor postoperative outcomes, including increased rates of readmission, delirium, falls, and mortality. However, very little work has been done to improve perioperative mental health. In particular, there have been limited systematic efforts that identify evidence-based behavioral and pharmacological strategies that were originally developed for depression and anxiety in otherwise medically well psychiatric patients. A mental health intervention bundle, composed of behavioral and pharmacological strategies, can mitigate anxiety and depression symptoms during the perioperative period. However, lacking is conclusive evidence on effectiveness of such an intervention bundle focused on the delivery of perioperative mental health care in older surgical patients. Towards this end, the investigators will develop and test an intervention bundle that encompasses: (1) behavioral activation, and (2) medication optimization.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
A multi- and mixed-method adaptation study of a patient-centered perioperative mental health intervention bundle.
Abraham J, Meng A, Baumann A, Holzer KJ, et al · · 2023 · cited 13× · PMID 37891574 · DOI 10.1186/s12913-023-10186-3 -
Perioperative mental health intervention bundle for older surgical patients: protocol for an intervention development and feasibility study.
Abraham J, Holzer KJ, Lenard EM, Freedland KE, et al · · 2022 · cited 12× · PMID 35998971 · DOI 10.1136/bmjopen-2022-062398
Verify or expand the search:
- PubMed search for NCT05110690
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Behavioral Activation
Trials testing the same drug.
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- NCT06273995 — Telehealth Behavioral Activation for Teens · NA · recruiting
- NCT05685511 — Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing O · NA · completed
- NCT05574127 — A Study of Brief Behavioral Activation for the Treatment of Depression in Older Adult Cancer Survivors · Phase 2 · active not recruiting
Other recruiting trials for Older Adults
Currently open trials in the same condition.
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Other Washington University School of Medicine trials
Trials by the same sponsor.
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- NCT07313592 — Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients · not yet recruiting
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05110690 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Washington University School of Medicine
- Last refreshed: 18 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05110690.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing