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Medication optimization
Medication optimization is a clinical practice framework aimed at improving therapeutic outcomes by systematically reviewing, adjusting, and personalizing drug regimens for individual patients.
At a glance
| Generic name | Medication optimization |
|---|---|
| Sponsor | VA Office of Research and Development |
| Modality | Small molecule |
| Phase | FDA-approved |
Mechanism of action
This is not a discrete pharmaceutical agent but rather a healthcare delivery intervention developed by the VA Office of Research and Development. It involves evidence-based assessment of medication appropriateness, dosing, drug-drug interactions, and deprescribing to enhance efficacy and safety. The approach is typically applied across multiple therapeutic areas and patient populations.
Approved indications
Common side effects
Key clinical trials
- A Machine Learning Prediction Model for Postoperative Acute Kidney Injury in Non-Cardiac Surgery Patients
- A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events (NA)
- A Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of LRK-4189 Alone and in Combination in Patients With Solid Tumors (PHASE1, PHASE2)
- A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma (PHASE1)
- INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients (NA)
- Optimization of Minocycline for Helicobacter Pylori Rescue Treatment (PHASE4)
- Advanced Functional and Structural MRI Techniques for Neuropharmacological Imaging (NA)
- A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Medication optimization CI brief — competitive landscape report
- Medication optimization updates RSS · CI watch RSS
- VA Office of Research and Development portfolio CI