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NCT05105074
Does the Use of Intrathecal Morphine Increase the Length of Hospital Stay in Fast Track Orthopedic Procedures?
NA trial testing Intrathecal Morphine in Arthropathy of Knee in 104 participants. Completed in 30 October 2021.
1 October 2021
Quick facts
| Lead sponsor | Samuel Lunenfeld Research Institute, Mount Sinai Hospital |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | supportive care |
| Enrollment | 104 |
| Start date | 19 January 2019 |
| Primary completion | 1 October 2021 |
| Estimated completion | 30 October 2021 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Intrathecal Morphine — full drug profile →
- Placebo
Conditions studied
- Arthropathy of Knee — all drugs for Arthropathy of Knee →
- Arthropathy of Hip — all drugs for Arthropathy of Hip →
Sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Who can join
Adults 18 to 85, any sex, with Arthropathy of Knee or Arthropathy of Hip. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a clinical trial of intrathecal morphine for patients Patient with primary as well as revision knee and hip arthroplasty under regional anesthesia. This study would include a total of 134 patients. It is the intention to randomize these patients postoperatively into 2 groups of patients: Group 1 - Patients will receive intrathecal morphine 100 mcg in addition to the standard dose of bupivacaine and 15 mcg of fentanyl for spinal anesthesia. Group 2 - Patients will not receive intrathecal morphine. Patients will receive only bupivacaine and 15 mcg of fentanyl for spinal anesthesia. It is postulated that the use of intrathecal morphine may be associated with an increase length of stay in the hospital.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05105074
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Intrathecal Morphine
Trials testing the same drug.
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- NCT07231926 — Intrathecal Morphine for Recovery and Outcomes After VATS · NA · recruiting
- NCT07232108 — Intrathecal Morphine Versus Trocar-Site and Intraperitoneal Bupivacaine for Quality of Recovery After Laparoscopic Hyste · NA · recruiting
- NCT07203794 — Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cho · NA · not yet recruiting
- NCT07123740 — Comparison of the Postoperative Analgesic Effects of ITM and Bi-level ESPB in Liver Transplantation Donors · NA · recruiting
Other recruiting trials for Arthropathy of Knee
Currently open trials in the same condition.
- NCT07180953 — Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty · Phase 4 · recruiting
- NCT05290818 — Total Versus Robotic Assisted Unicompartmental Knee Replacement · NA · recruiting
- NCT06832995 — Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthroplasties · active not recruiting
- NCT03869996 — Total Knee Arthroplasty: Fast Track Protocol is the Future? · NA · recruiting
- NCT03674697 — The Effect of Light Therapy on Post-Surgical Pain · NA · active not recruiting
Other Samuel Lunenfeld Research Institute, Mount Sinai Hospital trials
Trials by the same sponsor.
- NCT06589687 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery · completed
- NCT06589661 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During and After Unexpected Cesarean Delivery · completed
- NCT06368583 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' and Providers' Experience During Neuraxial Labour Analges · completed
- NCT06368570 — The Patient AS EDUcator in Anesthesia: Exploring the Patients' Experience During Routine Cesarean Delivery · completed
- NCT06318715 — Modified Deep Extubation vs. Standard Awake Extubation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05105074 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Samuel Lunenfeld Research Institute, Mount Sinai Hospital
- Last refreshed: 12 May 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05105074.
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