Last reviewed · How we verify
NCT06832995: PAMTA
Incidence and Risk Factors for Post-Anesthetic Morphine Titration in Recovery Room After Hip and Knee Arthroplasties
trial testing IV morphine administered during the PACU stay in Arthropathy of Hip in 300 participants. Participants enrolled and being followed up; not accepting new ones.
31 December 2025
Quick facts
| Lead sponsor | Hôpital Privé Sévigné |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 300 |
| Start date | 1 April 2024 |
| Primary completion | 31 December 2025 |
| Estimated completion | 28 February 2026 |
| Sites | 1 location across France |
Drugs / interventions tested
- IV morphine administered during the PACU stay — full drug profile →
Conditions studied
- Arthropathy of Hip — all drugs for Arthropathy of Hip →
- Arthropathy of Knee — all drugs for Arthropathy of Knee →
Sponsor
Hôpital Privé Sévigné — full company profile →
Who can join
18 and older, any sex, with Arthropathy of Hip or Arthropathy of Knee. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Despite the use of multimodal analgesia combining nerve block (NB) and systemic analgesia, intravenous (IV) morphine titration in the post-anesthetic care unit (PACU) after total hip (THA) and knee (TKA) arthroplasty is required to relieve early moderate-to-severe pain. Sedation occurrence during titration and a VAS score higher than 60/100mm are two independent risk factors for postoperative pain during hospitalization. The association of NB and multimodal analgesia constitutes the reference in evidence-based recommendations. An adductor or femoral triangle block, alone or associated with periarticular infiltration, is recommended during TKA. During THA, NB associated with surgical periarticular infiltration improves analgesia and rehabilitation This study aims to identify the incidence and risk factors of morphine titration in PACU after lower limb arthroplasty performed by 5 experienced surgeons and using a multimodal analgesic procedure
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06832995
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Arthropathy of Hip
Currently open trials in the same condition.
- NCT07327372 — PENG Block With Dexmedetomidine in Older Adults · NA · recruiting
- NCT05649007 — Post-marketing Surveillance Study of the Saphir Stem in Primary Hip Surgery · recruiting
- NCT05647629 — Observational Study of the Development of Low Back Pain After Total Hip Arthroplasty. · recruiting
Other Hôpital Privé Sévigné trials
Trials by the same sponsor.
- NCT04794608 — Hypnosis in Virtual Reality in Patients in Protector Isolation Room for Aplasia in Clinical Hematology. · NA · completed
- NCT04112277 — Observational Prospective Study of Opiate-free Anesthesia for Anterior Total Hip Replacement · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06832995 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hôpital Privé Sévigné
- Last refreshed: 18 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06832995.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing