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NCT07203794: ITM-ESP-IPLA
Analgesic Efficacy of Bupivacaine Infiltration, Erector Spinae Plane Block, and Intrathecal Morphine in Laparoscopic Cholecystectomy
NA trial testing Bupivacaine Infiltration in Postoperative Pain Management in 132 participants. Not yet recruiting.
1 April 2026
Quick facts
| Lead sponsor | Ataturk University |
|---|---|
| Phase | NA |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 132 |
| Start date | 1 December 2025 |
| Primary completion | 1 April 2026 |
| Estimated completion | 2 April 2026 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Bupivacaine Infiltration
- Erector Spinae Plane Block — full drug profile →
- Intrathecal Morphine — full drug profile →
Conditions studied
- Postoperative Pain Management — all drugs for Postoperative Pain Management →
- Cholecystectomy, Laparoscopic — all drugs for Cholecystectomy, Laparoscopic →
Sponsor
Ataturk University
Who can join
Adults 18 to 65, any sex, with Postoperative Pain Management or Cholecystectomy, Laparoscopic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study is designed to compare three different methods of pain control after laparoscopic gallbladder surgery (laparoscopic cholecystectomy). Although this surgery is minimally invasive, participants often experience different types of pain after the operation, such as pain at the incision site, pain inside the abdomen, and shoulder pain caused by the gas used during surgery. The investigators will compare three commonly used pain relief techniques: Local infiltration - injecting a numbing medicine (bupivacaine) into the gallbladder bed and at the sites where the surgical instruments are placed. Erector spinae plane (ESP) block - an ultrasound-guided nerve block performed in the back to reduce both abdominal and incisional pain. Intrathecal morphine - a very small dose of morphine given into the spinal fluid before surgery to provide long-lasting pain relief. The goal is to determine which method provides the best pain control, reduces the need for opioid medications, and improves recovery after surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07203794
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07203794 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Ataturk University
- Last refreshed: 25 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07203794.
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