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NCT05044741
Risk Factors of Perforated HSCR in Neonates
trial testing Emergency surgical enterostomy in Hirschsprung Disease in 600 participants. Completed in 31 December 2019.
31 December 2010
Quick facts
| Lead sponsor | Tongji Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 600 |
| Start date | 1 January 2006 |
| Primary completion | 31 December 2010 |
| Estimated completion | 31 December 2019 |
Drugs / interventions tested
- Emergency surgical enterostomy
Conditions studied
- Hirschsprung Disease — all drugs for Hirschsprung Disease →
- Bowel; Perforation, Fetus or Newborn — all drugs for Bowel; Perforation, Fetus or Newborn →
Sponsor
Tongji Hospital
Who can join
Adults 0 Days to 30 Days, any sex, with Hirschsprung Disease or Bowel; Perforation, Fetus or Newborn. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Hirschsprung's disease (HSCR) is a common digestive malformation with radiographic evidence of distal bowel obstruction and clinical signs of abdominal distension, vomiting, constipation, and failure to pass meconium. Bowel perforation (perforated HSCR) is a very serious complication of HSCR, but if this occurs it is most often in the neonatal period. The current study collected information on all cases diagnosed with perforated HSCR from multi-centers in China over 10 years, the aim was to evaluate the clinical features of perforated HSCR, and investigate possible risk factors for perforated HSCR in neonates.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Enterocolitis Is a Risk Factor for Bowel Perforation in Neonates With Hirschsprung's Disease: A Retrospective Multicenter Study.
Zhu T, Zhang G, Meng X, Yang J, et al · · 2022 · cited 9× · PMID 35198516 · DOI 10.3389/fped.2022.807607
Verify or expand the search:
- PubMed search for NCT05044741
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Tongji Hospital trials
Trials by the same sponsor.
- NCT07537946 — Local Consolidation After Sintilimab Plus Lenvatinib for Metastatic Liver Cancer · Phase 3 · not yet recruiting
- NCT07537972 — Denosumab Strategy for Liver Cancer With Bone Metastases · Phase 2 · not yet recruiting
- NCT07537959 — Surgery Plus Systemic Therapy for Liver Cancer With Extrahepatic Metastases · NA · not yet recruiting
- NCT07527260 — Effects of Adenoidectomy on Symptoms and IgE Levels in Children With AR · NA · not yet recruiting
- NCT07524712 — Effects of Energy Versus Mechanical Surgical Devices on Postoperative Cough · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05044741 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Tongji Hospital
- Last refreshed: 16 September 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05044741.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing