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NCT07519915: SMART-GUT
Improvement of Understanding of Pediatric Sacral Neuromodulation: Therapeutic Strategies and Outcome Variables
NA trial testing SNM/MRI/EMG in Gastrointestinal Motility Disorders in Children in 25 participants. Currently enrolling.
31 December 2028
Quick facts
| Lead sponsor | Friedrich-Alexander-Universität Erlangen-Nürnberg |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | sequential |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 25 |
| Start date | 1 July 2018 |
| Primary completion | 31 December 2028 |
| Estimated completion | 31 December 2029 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- SNM/MRI/EMG
Conditions studied
- Gastrointestinal Motility Disorders in Children — all drugs for Gastrointestinal Motility Disorders in Children →
- Hirschsprung Disease — all drugs for Hirschsprung Disease →
- Constipation - Functional — all drugs for Constipation - Functional →
Sponsor
Friedrich-Alexander-Universität Erlangen-Nürnberg — full company profile →
Who can join
Adults 3 to 18, any sex, with Gastrointestinal Motility Disorders in Children or Hirschsprung Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this study is to learn about the effects of sacral neuromodulation in pediatric patients with gastrointestinal motility disorders. By combining advanced neuroimaging, patient-specific biophysical modeling, electrophysiological characterization, and clinical translation, the SMART-GUT project establishes a comprehensive framework to systematically investigate neuromodulation in this pediatric population. This integrative approach enables a direct link between mechanism, targeting, and clinical outcome.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07519915
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Gastrointestinal Motility Disorders in Children
Currently open trials in the same condition.
- NCT05880199 — BSGM to Evaluate Patients With GI Symptoms · recruiting
Other Friedrich-Alexander-Universität Erlangen-Nürnberg trials
Trials by the same sponsor.
- NCT06404437 — Detection of Aortic Stenosis With Smartphone Auscultation Using Machine Learning (HEARTBEAT-Pilot) · active not recruiting
- NCT05666609 — Fistula-in-ano in Infants and Children · NA · recruiting
- NCT07314879 — Impact of Interventional Revascularization on the Physiological Assessment of Bystander Coronary Lesions by FFR · completed
- NCT04713085 — Sacral Neuromodulation in Children and Adolescents · NA · completed
- NCT04710433 — Non-invasive Sacral Nerve Stimulation in Children and Adolescents With Chronic Constipation · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07519915 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Friedrich-Alexander-Universität Erlangen-Nürnberg
- Last refreshed: 9 April 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07519915.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing