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NCT04949659: LoMePneu
Low vs Medium Pressure Pneumoperitoneum
NA trial testing Laparoscopic appendectomy in Appendicitis Acute in 250 participants. Completed in 31 January 2025.
31 January 2025
Quick facts
| Lead sponsor | University Children's Hospital, Zurich |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 250 |
| Start date | 27 September 2021 |
| Primary completion | 31 January 2025 |
| Estimated completion | 31 January 2025 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Laparoscopic appendectomy
Conditions studied
- Appendicitis Acute — all drugs for Appendicitis Acute →
Sponsor
University Children's Hospital, Zurich
Who can join
5 and older, any sex, with Appendicitis Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to asses whether the pressure used for the pneumoperitoneum during laparoscopic surgery in children affects their postoperative pain levels.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04949659
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Laparoscopic appendectomy
Trials testing the same drug.
- NCT04519086 — The Optimization of a Low-dose CT Protocol in Patients With Suspected Uncomplicated Acute Appendicitis and BMI >30 · NA · suspended
- NCT04755179 — Identification of the Optimal Treatment Strategy for Complex Appendicitis in the Pediatric Population · completed
- NCT03912714 — COlonic Salvage by Therapeutic Appendectomy. · NA · completed
- NCT04895163 — Acute Appendicitis in Foreign Workers of Northern Israel · completed
- NCT03754777 — Modified Enhanced Recovery Program in Emergency Surgery (MERES) · NA · completed
Other recruiting trials for Appendicitis Acute
Currently open trials in the same condition.
- NCT07521969 — Out-patiente Management for Gangrenous Acute Appendicitis: The PENDI-CSI II Randomized Clinical Trial. · NA · recruiting
- NCT06815822 — Prevention of Postoperative Hernias in Emergency Surgery · recruiting
- NCT06948071 — Enhanced Recovery After Surgery (ERAS) for Complicated Appendicitis · NA · recruiting
- NCT06762275 — The Impact of a Diagnostic Strategy for Acute Appendicitis in Children With Acute Abdominal Pain in Primary Care · NA · recruiting
- NCT06395636 — Early Detection of Infection Using the Fitbit in Pediatric Surgical Patients · NA · recruiting
Other University Children's Hospital, Zurich trials
Trials by the same sponsor.
- NCT07415577 — The Use of Cultured (Dermal) Epithelial Autografts in Severely Burned Patients · not yet recruiting
- NCT06852313 — Save the Ovaries - Surgical Management of Simple Ovarian Cysts in Children and Adolescents · NA · recruiting
- NCT07368166 — Development of the PTSD-iMPACT to Measure PTSD-Related Functional Impairment in Children and Adolescents - A Validation · recruiting
- NCT06950047 — PediLoc® Blade Plate in Distal Femoral Osteotomies · completed
- NCT05971264 — Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04949659 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Children's Hospital, Zurich
- Last refreshed: 20 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04949659.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing