NCT04908969: TICNET

Internet-based Cognitive Behavioral Therapy for Chronic Tic Disorder and Tourette's Disorder: a Feasibility Trial

Status unknown NA Last updated 28 October 2022

What this trial tests

NA trial testing Internet-delivered Cognitive Behavior Therapy for Chronic Tic Dosorder/Tourette Disorder in Chronic Tic Disorder in 30 participants. Status unknown.

Timeline

15 April 2021

Primary endpoint
23 June 2023

23 August 2023

Quick facts

Lead sponsor	Karolinska Institutet
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	30
Start date	15 April 2021
Primary completion	23 June 2023
Estimated completion	23 August 2023
Sites	1 location across Sweden

Drugs / interventions tested

• Internet-delivered Cognitive Behavior Therapy for Chronic Tic Dosorder/Tourette Disorder

Conditions studied

• Chronic Tic Disorder — all drugs for Chronic Tic Disorder →
• Tourette Syndrome — all drugs for Tourette Syndrome →

Sponsor

Karolinska Institutet

Who can join

18 and older, any sex, with Chronic Tic Disorder or Tourette Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Tic disorders, including Tourette's Disorder (TD) and Chronic Motor or Vocal Tic Disorder (CTD), are neurodevelopmental motor disorders characterised by motor and/or vocal tics. TD/CTD are impairing conditions with onset during childhood that often persist into adulthood. Behaviour therapy (BT) is an effective treatment for TD/CTD and is recommended as a first-line intervention in both in children and in adults. However, most adults with TD/CTD do not have access to BT due to a lack of trained professionals and geographical barriers. The objective of the study is to adapt and extend existing face-to-face BT treatment protocols for adults with TD/CTD to an internet-delivered format and evaluate its feasibility and preliminary efficacy. A total of 30 adult TD/CTD adult patients deemed eligible for the study through the recruitment process involving both psychologist and physician assessment will be enrolled in the project. The 8-modues treatment program, mainly based on exposure with response prevention with addition of other techniques will be made available for the participants in a secure treatment platform. The participants will keep in touch with a therapist using two-ways written communication in the same platform. The therapist's role will be to introduce the treatment and its modules, give feedback on the homework assignments and open the new modules as well as monitor the participants psychiatric symptoms and activity in the plattform. The measures will include tic severity secifically and disease severity in general, anxiety and depression symptoms, quality of life, treatment credibility and therapeutic alliance. The measures will be administrated at baseline, min- and post-tretment, as well at 3 and 12 months follow-up. Upon completion, this project will be the first crucial step towards the implementation of internet-delivered behaviour therapy (I-BT) for adults with TD/CTD in regular health care.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.