Who is sponsoring NCT04904107?

NCT04904107 is sponsored by VieCuri Medical Centre.

What drugs are being tested in NCT04904107?

Interventions in NCT04904107: modified HEART score (including POC hs cTnI analysis), Standard care and triage according to the local (EMT)protocol..

What condition does NCT04904107 study?

NCT04904107 studies Chest Pain, Acute Coronary Syndrome, Myocardial Infarction, Myocardial Ischemia, Heart Attack.

Is NCT04904107 still recruiting?

NCT04904107 is currently status unknown. Last updated 10 June 2022.

Last reviewed 2022-06-10 · How we verify

NCT04904107: URGENT2

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Improving the Accuracy of Referrals of Patients With Chest Pain

Status unknown NA Last updated 10 June 2022

What this trial tests

NA trial testing modified HEART score (including POC hs cTnI analysis) in Chest Pain in 852 participants. Status unknown.

Timeline

4 July 2021

Primary endpoint
1 June 2023

1 June 2024

Quick facts

Lead sponsor	VieCuri Medical Centre
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	diagnostic
Enrollment	852
Start date	4 July 2021
Primary completion	1 June 2023
Estimated completion	1 June 2024
Sites	2 locations across Netherlands

Drugs / interventions tested

modified HEART score (including POC hs cTnI analysis)
Standard care and triage according to the local (EMT)protocol.

Conditions studied

Chest Pain — all drugs for Chest Pain →
Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Myocardial Infarction — all drugs for Myocardial Infarction →
Myocardial Ischemia — all drugs for Myocardial Ischemia →

Sponsor

VieCuri Medical Centre

Who can join

18 and older, any sex, with Chest Pain or Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a multicenter, prospective, investigator-initiated, randomized controlled trial aiming to reduce the percentage of non-cardiac chest pain (NCCP) patients admitted to the cardiac emergency department (ED) by performing the modified HEART score by emergency medical transport (EMT) personnel.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for a multicentre randomised controlled trial.
Frenk LDS, Rahel BM, de Vos CB, van Osch FHM, et al · · 2024 · PMID 39806626 · DOI 10.1136/bmjopen-2024-084139

Verify or expand the search:

Other recruiting trials for Chest Pain

Currently open trials in the same condition.

NCT06853626 — One-hoUr Troponin Using a High-sensitivity Point-Of-Care Assay in Emergency Primary Care · NA · recruiting
NCT07247669 — Evaluation and Optimization of Telephone Triage Using Artificial Intelligence (AI) Models for the Detection of Demands f · active not recruiting
NCT06239974 — Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM) · NA · recruiting
NCT06520150 — Evaluation of the Effectiveness of Two Methods of Regional Anesthesia During S-ICD Implantation Procedure. · NA · recruiting
NCT07435168 — CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis · NA · recruiting

Other VieCuri Medical Centre trials

Trials by the same sponsor.

NCT06520085 — Optimizing Recovery After Reverse Shoulder Arthroplasty With a Personalized Mobile Health Application · NA · not yet recruiting
NCT05331196 — Prognostic Value of Effort-independent Cardiopulmonary Exercise Test Variables for Postoperative Complications After Ele · completed
NCT05483179 — Association Between New Effort-independent Cardiopulmonary Exercise Test Variables and Postoperative Complications After · completed
NCT05353127 — Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment · completed
NCT04458155 — Li-Hep vs. Non-Li-Hep Coated Transfer Device · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04904107 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by VieCuri Medical Centre
Last refreshed: 10 June 2022

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04904107.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing