Last reviewed · How we verify
NCT05331196
Prognostic Value of Effort-independent Cardiopulmonary Exercise Test Variables for Postoperative Complications After Elective Colorectal Surgery
trial testing Preoperative cardiopulmonary exercise tetsing in Colorectal Cancer in 114 participants. Completed in 15 October 2022.
15 July 2022
Quick facts
| Lead sponsor | VieCuri Medical Centre |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 114 |
| Start date | 15 April 2022 |
| Primary completion | 15 July 2022 |
| Estimated completion | 15 October 2022 |
| Sites | 1 location across Netherlands |
Drugs / interventions tested
- Preoperative cardiopulmonary exercise tetsing
Conditions studied
- Colorectal Cancer — all drugs for Colorectal Cancer →
Sponsor
VieCuri Medical Centre
Who can join
18 and older, any sex, with Colorectal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
A cardiopulmonary exercise test (CPET) is increasingly used for preoperative risk assessment. Oxygen uptake (VO2) at peak exercise (VO2peak) and VO2 at the ventilatory anaerobic threshold (VO2VAT) are the most commonly used preoperative CPET variables that are associated with postoperative outcomes following colorectal cancer surgery. The aim of this study is to investigate the association between preoperative submaximal and effort-independent CPET variables and postoperative outcomes in colorectal cancer surgery. Specifically, the slope of the relation between minute ventilation and carbon dioxide production (VE/VCO2-slope) and the oxygen uptake efficiency slope (OUES) will be investigated.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A retrospective analysis of the association of effort-independent cardiopulmonary exercise test variables with postoperative complications in patients who underwent elective colorectal surgery.
Franssen RFW, Berkel AEM, Ten Cate DWG, van der Palen J, et al · · 2023 · PMID 38093118 · DOI 10.1007/s00423-023-03197-5
Verify or expand the search:
- PubMed search for NCT05331196
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Colorectal Cancer
Currently open trials in the same condition.
- NCT07152821 — Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcino · Phase 3 · recruiting
- NCT07353645 — KRAS Neoantigen Nanovaccine as Adjuvant Therapy for Colorectal Cancer/Pancreatic Cancer · Phase 1, PHASE2 · recruiting
- NCT07432633 — [18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications · Phase 1, PHASE2 · recruiting
- NCT07523919 — Functional and Respiratory Determinants of Long-Term Colorectal Cancer Outcomes · recruiting
- NCT07529301 — Functional and Respiratory Predictors of Early Postoperative Outcomes · recruiting
Other VieCuri Medical Centre trials
Trials by the same sponsor.
- NCT06520085 — Optimizing Recovery After Reverse Shoulder Arthroplasty With a Personalized Mobile Health Application · NA · not yet recruiting
- NCT05483179 — Association Between New Effort-independent Cardiopulmonary Exercise Test Variables and Postoperative Complications After · completed
- NCT05353127 — Cardiopulmonary Exercise Test Data Averaging Methods and Preoperative Risk Assessment · completed
- NCT04904107 — Improving the Accuracy of Referrals of Patients With Chest Pain · NA · unknown
- NCT04458155 — Li-Hep vs. Non-Li-Hep Coated Transfer Device · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05331196 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VieCuri Medical Centre
- Last refreshed: 23 November 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05331196.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing