Last reviewed · How we verify
NCT04871100
Integrated CBT to Improve Functioning in Veterans With Anxiety and Substance Use
NA trial testing Unified Protocol- Alcohol in Anxiety Disorder in 40 participants. Currently enrolling.
29 May 2026
Quick facts
| Lead sponsor | VA Office of Research and Development |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 March 2023 |
| Primary completion | 29 May 2026 |
| Estimated completion | 1 October 2026 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Unified Protocol- Alcohol
- Usual care
Conditions studied
- Anxiety Disorder — all drugs for Anxiety Disorder →
- Posttraumatic Stress Disorder — all drugs for Posttraumatic Stress Disorder →
- Hazardous Drinking — all drugs for Hazardous Drinking →
Sponsor
VA Office of Research and Development — full company profile →
Who can join
18 and older, any sex, with Anxiety Disorder or Posttraumatic Stress Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Individual with anxiety and post-traumatic stress disorder often use alcohol in ways that could cause them harm. Treating both mental health concerns and alcohol use at the same time can help reduce difficulties engaging in multiple treatments. The investigators are evaluating how a cognitive behavioral therapy program that helps Veterans with anxiety, posttraumatic stress disorder, and alcohol use at the same time can help improve the participants lives.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Automating Clinical Trial Matches Via Natural Language Processing of Synthetic Electronic Health Records and Clinical Trial Eligibility Criteria.
Murcia VM, Aggarwal V, Pesaladinne N, Thammineni R, et al · · 2024 · cited 7× · PMID 38827083
Verify or expand the search:
- PubMed search for NCT04871100
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Anxiety Disorder
Currently open trials in the same condition.
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- NCT07045818 — DLPFC and Sympathetic Reactivity in RPL With Anxiety · recruiting
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- NCT06333925 — Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study · NA · active not recruiting
Other VA Office of Research and Development trials
Trials by the same sponsor.
- NCT07456150 — Personalizing Veteran Pain Care: Adapting Coaching Interventions to Support Maintenance of Self-Care · Phase 1 · not yet recruiting
- NCT06746727 — The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veteran · NA · not yet recruiting
- NCT07362576 — Perinatal Peer Support for Veterans With Serious Mental Illness · NA · not yet recruiting
- NCT06766331 — Integrated Care Versus Usual Care for Opioid Use Disorder and Infectious Diseases in Veterans · NA · not yet recruiting
- NCT07397195 — ACT for Veterans With IBD and Mental Health Challenges · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04871100 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by VA Office of Research and Development
- Last refreshed: 9 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04871100.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing