Who is sponsoring NCT04725773?

NCT04725773 is sponsored by University of Florida.

What drugs are being tested in NCT04725773?

Interventions in NCT04725773: Deep brain stimulation effect on apraxia.

What condition does NCT04725773 study?

NCT04725773 studies Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor.

Is NCT04725773 still recruiting?

NCT04725773 is currently terminated. Last updated 16 July 2025.

Last reviewed 2025-07-16 · How we verify

NCT04725773: Apraxia DBS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation

Terminated Last updated 16 July 2025

What this trial tests

trial testing Deep brain stimulation effect on apraxia in Deep Brain Stimulation in 2 participants. Terminated before completion.

Timeline

1 June 2021

Primary endpoint
28 January 2024

28 January 2024

Quick facts

Lead sponsor	University of Florida
Status	Terminated
Study type	OBSERVATIONAL
Enrollment	2
Start date	1 June 2021
Primary completion	28 January 2024
Estimated completion	28 January 2024
Sites	1 location across United States

Drugs / interventions tested

Deep brain stimulation effect on apraxia

Conditions studied

Deep Brain Stimulation — all drugs for Deep Brain Stimulation →
Parkinson Disease — all drugs for Parkinson Disease →
Apraxia, Motor — all drugs for Apraxia, Motor →

Sponsor

University of Florida

Who can join

Adults 18 to 80, any sex, with Deep Brain Stimulation or Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Deep brain stimulation (DBS) of the subthalamic nucleus or globus pallidus internus can improve motor symptoms Parkinson's disease (PD). However, it is not known whether DBS can help reduce the signs and symptoms of the limb-kinetic, ideomotor or ideational apraxia associated with PD or if apraxia can exist as a stimulation induced side effect from DBS therapy. In this study, we look to conduct a pilot study to examine the feasibility of characterizing the prevalence of apraxia in PD patients with chronic, stable DBS.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Deep Brain Stimulation for the Management of Refractory Neurological Disorders: A Comprehensive Review.
Rissardo JP, Vora NM, Tariq I, Mujtaba A, et al · · 2023 · cited 17× · PMID 38004040 · DOI 10.3390/medicina59111991

Verify or expand the search:

Other recruiting trials for Deep Brain Stimulation

Currently open trials in the same condition.

NCT07376278 — Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease · recruiting
NCT06909045 — Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease · NA · recruiting
NCT07417280 — LIFUS For Neurological Disorders · NA · recruiting
NCT07176494 — Revision of Deep Brain Stimulator in Patients With Parkinson's Disease · NA · recruiting
NCT06960096 — Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study · recruiting

Other University of Florida trials

Trials by the same sponsor.

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NCT07507214 — Optimized, Neuroplasticity-Enhanced-Depression (ONE-D) Transcranial Magnetic Stimulation (TMS) Treatment for Female Athl · Phase 2, PHASE3 · not yet recruiting
NCT07492316 — RNA-lipid Particle (RNA-LP) Vaccines for Recurrent/Progressive Medulloblastoma (MB) · Phase 1 · not yet recruiting
NCT06670794 — Using Ecological Momentary Data to Inform a Web Intervention for Romantic Partners Concerned About Their Loved Ones' Dri · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04725773 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Florida
Last refreshed: 16 July 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04725773.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing