Last reviewed · How we verify
NCT07376278
Predictors of Clinical Outcomes of Deep Brain Stimulation in Parkinson's Disease
trial testing DBS in Deep Brain Stimulation in 30 participants. Currently enrolling.
1 February 2036
Quick facts
| Lead sponsor | Hong Kong University of Science and Technology |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 30 |
| Start date | 5 February 2026 |
| Primary completion | 1 February 2036 |
| Estimated completion | 1 February 2038 |
| Sites | 1 location across Hong Kong |
Drugs / interventions tested
- DBS
Conditions studied
- Deep Brain Stimulation — all drugs for Deep Brain Stimulation →
- PARKINSON DISEASE (Disorder) — all drugs for PARKINSON DISEASE (Disorder) →
Sponsor
Hong Kong University of Science and Technology
Who can join
Adults 18 to 75, any sex, with Deep Brain Stimulation or PARKINSON DISEASE (Disorder). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to identify factors in blood that are associated with response to deep brain stimulation (DBS) surgery in patients with Parkinson's disease. The main questions it aims to answer are: 1. What factors in blood (proteins and RNA) are associated with good vs poor response to DBS? 2. Are these factors able to predict response to DBS? 3. How do these factors change before and after DBS? Blood and leftover brain tissue (which spontaneously adhere to the surgical instruments) will be taken and routine clinical data (including scores from routine assessments) will be collected from consenting participants who undergo DBS.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT07376278
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of DBS
Trials testing the same drug.
- NCT07340073 — Coordinated Reset Deep Brain Stimulation for Parkinson's Disease · Phase 1 · not yet recruiting
- NCT06122675 — Cerebellar Deep Brain Stimulation for Movement Disorders in Cerebral Palsy in Children and Young Adults · NA · recruiting
- NCT05934747 — Aim 3 Particle Swarm Optimization PIGD · NA · recruiting
- NCT07325175 — Quantifying Motor Network Dynamics to Predict and Enhance Outcomes in Pediatric Dystonia · NA · recruiting
- NCT05959161 — Study on Brain Network Mechanism of Deep Brain Stimulation for Parkinson's Disease · not yet recruiting
Other recruiting trials for Deep Brain Stimulation
Currently open trials in the same condition.
- NCT06909045 — Adaptive vs. Continuous Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease · NA · recruiting
- NCT07417280 — LIFUS For Neurological Disorders · NA · recruiting
- NCT07176494 — Revision of Deep Brain Stimulator in Patients With Parkinson's Disease · NA · recruiting
- NCT06960096 — Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study · recruiting
- NCT07115394 — EEG Measurements to Capture DBS-induced Electric Potentials · recruiting
Other Hong Kong University of Science and Technology trials
Trials by the same sponsor.
- NCT07381751 — Artificial Intelligence-assisted MDS-UPDRS Assessment for Parkinson's Disease · not yet recruiting
- NCT07356700 — Deciphering the Factors of Longevity Through a Multi-Omics Study in Long-Lived Individuals in Hong Kong · not yet recruiting
- NCT07347574 — NeuroCare Community Project: A Community Based Prospective Observational Study for Early Alzheimer's Detection in HK · not yet recruiting
- NCT07064382 — VR-based Multi-dimensional Intervention on Cognitive Function, With AI-agents · NA · not yet recruiting
- NCT06934720 — VR-based Physical Activity and Reminiscence Therapy · Phase 1, PHASE2 · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT07376278 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hong Kong University of Science and Technology
- Last refreshed: 24 February 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT07376278.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing