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NCT06127550
taVNS for Letter Learning in Dyslexia
NA trial testing active taVNS in Dyslexia in 100 participants. Suspended.
1 August 2028
Quick facts
| Lead sponsor | University of Florida |
|---|---|
| Phase | NA |
| Status | Suspended |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 100 |
| Start date | 1 August 2026 |
| Primary completion | 1 August 2028 |
| Estimated completion | 1 September 2029 |
| Sites | 1 location across United States |
Drugs / interventions tested
- active taVNS
- sham taVNS
Conditions studied
- Dyslexia — all drugs for Dyslexia →
Sponsor
University of Florida
Who can join
Adults 10 to 12, any sex, with Dyslexia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a pilot study to establish feasibility of transcutaneous auricular vagus nerve stimulation (taVNS) for improving letter-learning in adolescents with dyslexia. The main goals of the study are to 1) evaluate whether children in this age range will tolerate low level stimulation over the course of multiple sessions, 2) determine whether low level taVNS improves novel letter learning in dyslexia, and 3) evaluate the effect of low level taVNS on the brain's response to letters. Participants will complete fMRI before training, immediately after training, and a few weeks after training ends. Training will consist of six 30-minute lessons during which participants will learn novel letter-sound relationships while receiving either active or sham taVNS. Researchers will compare stimulation conditions to determine effect of this device on learning and neural plasticity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06127550
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other trials of active taVNS
Trials testing the same drug.
- NCT05944575 — Effect of taVNS on Heart Rate in Persistent Atrial Fibrillation · NA · unknown
- NCT05852379 — Transcutaneous Auricular Vagus Nerve Stimulation in Spinal Cord Injury · NA · unknown
Other recruiting trials for Dyslexia
Currently open trials in the same condition.
- NCT07262853 — Dual Executive Function Training Package · NA · recruiting
- NCT06902610 — Examining the Medium-term Effect on Non Inferiority of the Previous Training With the DMD Poppins Clinical for Cognitive · recruiting
- NCT05996497 — Evaluation of Speech Rhythm Training in Dyslexic Readers Aged 7 to 9 Years · NA · recruiting
- NCT05780853 — A Game-based Neurodevelopmental Assessment for Young Children · recruiting
- NCT03285789 — Dyslexics' Visual Attention Field · NA · active not recruiting
Other University of Florida trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06127550 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Florida
- Last refreshed: 11 December 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06127550.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing