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NCT04713774
Bone Density and Vascular Calcifications Evolution After Renal Transplant
trial testing High-resolution peripheral quantitative CT scanner (HRpQCT) in Kidney Transplant; Complications in 50 participants. Currently enrolling.
12 December 2025
Quick facts
| Lead sponsor | University of Liege |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 1 September 2020 |
| Primary completion | 12 December 2025 |
| Estimated completion | 13 December 2026 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- High-resolution peripheral quantitative CT scanner (HRpQCT)
Conditions studied
- Kidney Transplant; Complications — all drugs for Kidney Transplant; Complications →
- Bone Loss — all drugs for Bone Loss →
Sponsor
University of Liege
Who can join
18 and older, any sex, with Kidney Transplant; Complications or Bone Loss. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators project is based on: * Assessment of bone architecture by high resolution peripheral scanner (HRpQCT) and bone densitometry (DEXA); * The non-invasive detection of vascular calcifications (by abdominal CT scanner) and bone abnormalities associated with kidney transplantation, as well as the analysis of evolution over time; * Longitudinal evaluation of nephrological clinical parameters (glomerular filtration rate, number and type of rejections, immunosuppressive medications) as well as biological and urinary parameters of mineral metabolism (parathormone, sclerostin, bone alkaline phosphatase) depending on the type and severity of bone abnormalities; * The evaluation of these nephrological clinical parameters and of the biological parameters of mineral metabolism depending on the extent and evolution of vascular calcifications but also on bone morphology; * The study of possible relationships between bone mass and muscle mass (and functioning)
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (WCO-IOF-ESCEO 2022).
· 2022 · cited 6× · PMID 36008648 · DOI 10.1007/s40520-022-02147-3
Verify or expand the search:
- PubMed search for NCT04713774
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04713774 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Liege
- Last refreshed: 18 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04713774.
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