NCT04698317 (RCT) is a Phase 2 clinical trial of open flap debridement in Chronic Periodontitis, sponsored by Tanta University.

Who is sponsoring NCT04698317?

NCT04698317 is sponsored by Tanta University.

What drugs are being tested in NCT04698317?

Interventions in NCT04698317: open flap debridement, use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors, use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone.

What condition does NCT04698317 study?

NCT04698317 studies Chronic Periodontitis, Intrabony Periodontal Defect, Concentrated Growth Factors.

Is NCT04698317 still recruiting?

NCT04698317 is currently completed. Last updated 4 October 2021.

Last reviewed 2021-10-04 · How we verify

NCT04698317: RCT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial

Completed Phase 2 Last updated 4 October 2021

What this trial tests

Phase 2 trial testing open flap debridement in Chronic Periodontitis in 40 participants. Completed in 1 July 2021.

Timeline

1 January 2021

Primary endpoint
1 July 2021

1 July 2021

Quick facts

Lead sponsor	Tanta University
Phase	Phase 2
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	40
Start date	1 January 2021
Primary completion	1 July 2021
Estimated completion	1 July 2021
Sites	1 location across Egypt

Drugs / interventions tested

open flap debridement — full drug profile →
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors
use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone

Conditions studied

Chronic Periodontitis — all drugs for Chronic Periodontitis →
Intrabony Periodontal Defect — all drugs for Intrabony Periodontal Defect →
Concentrated Growth Factors — all drugs for Concentrated Growth Factors →

Sponsor

Tanta University

Who can join

Adults 30 to 50, any sex, with Chronic Periodontitis or Intrabony Periodontal Defect. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This clinical study aimed to evaluate the efficacy of biodegradable gelatin sponge loaded with Beta-tricalcium phosphate socked in concentrated growth factors in the treatment of periodontal intra-bony defects, as compared with biodegradable gelatin/beta-tricalcium phosphate sponges alone.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of open flap debridement

Trials testing the same drug.

NCT06025955 — Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement. · NA · unknown
NCT06842511 — Effects of the Adjunctive Use of Hyaluronic Acid-based Gel in the Surgical Periodontal Treatment of Periodontitis · Phase 1, PHASE2 · completed
NCT04643288 — Nanocrystalline Hydroxyapatite Bone Substitute for Treating Periodontal Intrabony Defects · NA · completed
NCT03882138 — Influence of Gingival Biotype on the Outcome of Open Flap Debridement · NA · completed

Other recruiting trials for Chronic Periodontitis

Currently open trials in the same condition.

NCT06893107 — Study on Treatment Results and Bone Changes After Replanting Severely Affected Teeth - A Before-and-After Study. · NA · recruiting
NCT05275192 — Utilization of a Videoscope in Periodontal Regeneration · NA · recruiting
NCT03741374 — Minimally-invasive Non-surgical Therapy of Intrabony Defects · NA · active not recruiting
NCT03553095 — Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis · NA · active not recruiting

Other Tanta University trials

Trials by the same sponsor.

NCT07398651 — Apremilast and Adalimumab in Psoriatic Arthritis Patients · NA · not yet recruiting
NCT06966856 — This Randomized, Clinical Trial Evaluates the Efficacy of Oral Versus Sublingual Vitamin B12 Supplementation in Correcti · Phase 3 · not yet recruiting
NCT07334197 — Effect of Melatonin on Left Ventricular Reverse Remodeling and Inflammation in Peripartum Cardiomyopathy · NA · not yet recruiting
NCT07498998 — Glucocorticoid, Ozone and 5% Dextrose Local Injection for Pain Relief in Carpal Tunnel Syndrome · NA · not yet recruiting
NCT07114250 — Comparative Study Between Spinal Anesthesia Versus General Anesthesia in Supine Percutaneous Nephrolithotomy Operation · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT04698317 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Tanta University
Last refreshed: 4 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04698317.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing