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NCT04673877
Vancomycin Tissue Concentrations by Bier Block or Intravenous Administration
Phase 1 trial testing Systemic IV Vancomycin in Infection in 20 participants. Completed in 17 August 2022.
17 August 2022
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Phase | Phase 1 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 26 August 2021 |
| Primary completion | 17 August 2022 |
| Estimated completion | 17 August 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Systemic IV Vancomycin — full drug profile →
- Bier Block
- Vancomycin (vancomycin) — full drug profile →
Conditions studied
- Infection — all drugs for Infection →
- Hand Injury Wrist — all drugs for Hand Injury Wrist →
- Hand Injuries — all drugs for Hand Injuries →
- Hand Injuries and Disorders — all drugs for Hand Injuries and Disorders →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Infection or Hand Injury Wrist. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to determine whether or not giving a lower dose of antibiotics (Vancomycin) in the area where it is needed (upper extremity) is more effective at preventing infection than the current standard dose which is given intravenously (IV).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT04673877
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04673877 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 7 October 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04673877.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing