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NCT04659642
Attenuation of Airway and Cardiovascular Responses to Extubation in Chronic Smokers
EARLY_PHASE1 trial testing Dexmedetomidine Injection [Precedex] in Airway Responses in 66 participants. Status unknown.
6 March 2021
Quick facts
| Lead sponsor | National Cancer Institute, Egypt |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 66 |
| Start date | 30 November 2020 |
| Primary completion | 6 March 2021 |
| Estimated completion | 20 March 2021 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Dexmedetomidine Injection [Precedex] — full drug profile →
- Fentanyl Citrate Injection
- dexmedetomidine and fentanyl — full drug profile →
Conditions studied
- Airway Responses — all drugs for Airway Responses →
- Hemodynamic — all drugs for Hemodynamic →
Sponsor
National Cancer Institute, Egypt
Who can join
Adults 20 to 60, male only, with Airway Responses or Hemodynamic. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this blind comparative study was to compare the effects of dexmedetomidine, fentanyl and their combination on airway reflexes and hemodynamic responses to tracheal extubation in Adult chronic male smoking patients scheduled for abdominal surgeries (of average 2-3 hours duration).
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04659642
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT07434206 — Safety and Efficacy of Dexmedetomidine in Controlling Hemodynamics During Resection of Active Thyroid Secreting Tumors · Phase 2, PHASE3 · active not recruiting
- NCT05788393 — Opioid Sparing Analgesia Continuous Intraoperative Infusion of Dexmedetomidine Versus Lidocaine for Laparoscopic Cholecy · Phase 4 · completed
Other National Cancer Institute, Egypt trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04659642 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by National Cancer Institute, Egypt
- Last refreshed: 10 March 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04659642.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing