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NCT04651699
Non-Invasive Brain Stimulation for the Treatment of Parkinson´s Disease-related Pain
NA trial testing Active Transcranial Direct Current Stimulation in Parkinson Disease in 22 participants. Completed in 23 January 2023.
30 June 2022
Quick facts
| Lead sponsor | Universidad Francisco de Vitoria |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 22 |
| Start date | 3 May 2021 |
| Primary completion | 30 June 2022 |
| Estimated completion | 23 January 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- Active Transcranial Direct Current Stimulation
- Sham Transcranial Direct Current Stimulation
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
- Pain — all drugs for Pain →
Sponsor
Universidad Francisco de Vitoria — full company profile →
Who can join
18 and older, any sex, with Parkinson Disease or Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Pain is an under-reported but prevalent symptom in Parkinson´s Disease (PD), impacting patients' quality of life. Both pain and PD conditions cause cortical excitability reduction, but non-invasive brain stimulation is thought to be able to counteract it, resulting also effective in chronic pain conditions. The investigators in the present project aim to evaluate the efficacy of a novel brain stimulation protocol in the management of pain in PD patients during the ON state. The investigators hypothesize that active transcranial direct current stimulation (a-tDCS) over the Primary Motor Cortex (M1) can improve clinical pain and its central processing features.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
New Approaches Based on Non-Invasive Brain Stimulation and Mental Representation Techniques Targeting Pain in Parkinson's Disease Patients: Two Study Protocols for Two Randomized Controlled Trials.
González-Zamorano Y, Fernández-Carnero J, Sánchez-Cuesta FJ, Arroyo-Ferrer A, et al · · 2021 · cited 5× · PMID 33561080 · DOI 10.3390/brainsci11010065
Verify or expand the search:
- PubMed search for NCT04651699
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Active Transcranial Direct Current Stimulation
Trials testing the same drug.
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- NCT04683172 — Transcranial Direct-current Stimulation (tDCS) Efficacy in Refractory Cancer Pain. · NA · unknown
- NCT04119128 — tDCS for Fatigue in Sjogren's Syndrome · NA · completed
- NCT03184740 — Physical Performance and Analgesic Effects of tDCS in Primary Dysmenorrhea · NA · completed
Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
- NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
- NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
- NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
- NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other Universidad Francisco de Vitoria trials
Trials by the same sponsor.
- NCT07506343 — SDT-Based Intervention for Exercise Motivation in Female Students · NA · not yet recruiting
- NCT07452237 — Effects of Transcutaneous Neuromodulation and Cervical Exercise in Students With Chronic Nonspecific Cervical Pain · NA · not yet recruiting
- NCT07400900 — Effectiveness of a Standardised Stabilisation Exercise Protocol in Volleyball Players With Non-traumatic Shoulder Instab · NA · not yet recruiting
- NCT07334171 — Inspiratory Muscle Strength and Diaphragm Thickness in People With Shoulder Pain in Tennis Players · active not recruiting
- NCT07328334 — Longitudinal Assessment of Maximal Inspiratory Pressure and Functional Capacity Following Inspiratory Muscle Training in · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04651699 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Francisco de Vitoria
- Last refreshed: 26 January 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04651699.
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