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NCT04119128
tDCS for Fatigue in Sjogren's Syndrome
NA trial testing Active Transcranial Direct Current Stimulation in Sjogren's Syndrome in 36 participants. Completed in 1 April 2020.
1 April 2020
Quick facts
| Lead sponsor | Federal University of São Paulo |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 36 |
| Start date | 3 June 2019 |
| Primary completion | 1 April 2020 |
| Estimated completion | 1 April 2020 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Active Transcranial Direct Current Stimulation
- Sham Transcranial Direct Current Stimulation
Conditions studied
- Sjogren's Syndrome — all drugs for Sjogren's Syndrome →
Sponsor
Federal University of São Paulo
Who can join
Adults 18 to 65, female only, with Sjogren's Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sjogren's Syndrome (SS) is an autoimune disease of unknown etiology characterized by lymphocytic infiltration of the exocrine glands and other organs. patients usually presents with xerophthalmia, xerostomia, fatigue and other symptoms. Fatigue has often been reported as the biggest problem and the most difficult symptom patients have to deal with. Fatigue management in pSS is difficult. However, in other diseases such as Parkinson disease, post-polio syndrome and multiple sclerosis the use of Transcranial Direct Current Stimulation (tDCS) has recently been studied and has shown effectiveness. The overarching objective of this study is to examine the effect of a tDCS protocol in patients with pSS.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Transcranial direct current stimulation for fatigue in patients with Sjogren's syndrome: A randomized, double-blind pilot study.
Pinto ACPN, Piva SR, Vieira AGDS, Gomes SGCN, et al · · 2021 · cited 18× · PMID 33340767 · DOI 10.1016/j.brs.2020.12.004 -
Emerging treatment for Sjögren's disease: a review of recent phase II and III trials.
Fox RI, Fox CM, McCoy SS. · · 2023 · cited 9× · PMID 37127914 · DOI 10.1080/14728214.2023.2209720
Verify or expand the search:
- PubMed search for NCT04119128
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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- NCT03184740 — Physical Performance and Analgesic Effects of tDCS in Primary Dysmenorrhea · NA · completed
Other recruiting trials for Sjogren's Syndrome
Currently open trials in the same condition.
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- NCT07041099 — A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease · Phase 1 · recruiting
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Other Federal University of São Paulo trials
Trials by the same sponsor.
- NCT07376811 — Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome · NA · not yet recruiting
- NCT06805656 — Multi Interventional Approaches to Mitigate HIV Reservoirs Aiming the Sustained HIV Remission Without Antiretrovirals · Phase 2 · not yet recruiting
- NCT06970964 — Fermented Milk Drink With Lacticaseibacillus Paracasei Strain Shirota Helps Triathletes With Cold-Like Symptoms Before a · NA · completed
- NCT06905860 — Intra-articular Infiltration of Platelet-Rich Fibrin vs Corticosteroid in Mild to Moderate Knee Osteoarthritis · Phase 4 · not yet recruiting
- NCT06829992 — Effects of Applying Kinesio Tapping on Primary Dysmenorrhea in Football Players · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04119128 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Federal University of São Paulo
- Last refreshed: 11 May 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04119128.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing