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NCT04630834
Ibuprofen Plus Acetaminophen for Enhanced Pain Reduction
Phase 4 trial testing Ibuprofen in Pain, Acute in 100 participants. Status unknown.
20 June 2022
Quick facts
| Lead sponsor | New York City Health and Hospitals Corporation |
|---|---|
| Phase | Phase 4 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 100 |
| Start date | 30 March 2021 |
| Primary completion | 20 June 2022 |
| Estimated completion | 30 June 2022 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ibuprofen (ibuprofen) — full drug profile →
- Acetaminophen (Paracetamol) — full drug profile →
- Placebo
Conditions studied
- Pain, Acute — all drugs for Pain, Acute →
Sponsor
New York City Health and Hospitals Corporation
Who can join
Adults 3 to 20, any sex, with Pain, Acute. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Combination of analgesics with different modes of action have the potential to offer enhanced pain relief with reduced dosage. Ibuprofen and acetaminophen have different modes of action. Combination of ibuprofen and acetaminophen has shown enhanced analgesia in adult studies, with pediatric data limited to post-operative pain and dental pain. Our study objective is to evaluate the analgesic efficacy of oral acetaminophen plus ibuprofen versus ibuprofen plus placebo for the management of acute pain in a pediatric emergency department.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT04630834
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other New York City Health and Hospitals Corporation trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT04630834 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by New York City Health and Hospitals Corporation
- Last refreshed: 14 April 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT04630834.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing